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[173472_s_at] 3-keto-acyl-CoA thiolase

Description g2190266 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=Y57A10C.6 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=Y57A10C.6 /WP=CE18418 /CHR=2 /FEA=Genomic Cluster /DEF=3-keto-acyl-CoA thiolase
Cluster 6grp_highest_10_10 > 74      6grp_high1_10_10 > 57      4grp_highest_8_8 > 21      4grp_high_8_8 > 15      6grp_highest_nonorm > 37      6grp_total > 58      4grp_total > 16      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14162
1 2 3 4 range
A 3082.2
(-3)
P 		5432
(-2)
P 		8432.2
(-0.7)
P 		17177
(3)
P 		14095
B 3152.4
(-3)
P 		5519.4
(-2)
P 		7895
(-1)
P 		17244.4
(3)
P 		14092
C 3353.5
(-3)
P 		4914.1
(-2.3)
P 		7718.8
(-1)
P 		16760.7
(3)
P 		13407
avr 3196
(-3) 		5288.5
(-2.1) 		8015.3
(-0.9) 		17060.7
(3) 		13865

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 4815
1 2 3 4 5 6 range
A 6273.5
(1.7)
P 		4306.9
(-1.8)
P 		4816.2
(-0.9)
P 		3645.1
(-2.9)
P 		3603
(-3)
P 		7030.6
(3)
P 		3428
B 6489.2
(2.1)
P 		4529.7
(-2.4)
P 		4727.7
(-2)
P 		4474.3
(-2.6)
P 		4288.3
(-3)
P 		6892.6
(3)
P 		2604
C 5602.5
(-0.4)
P 		4567.2
(-1.7)
P 		4404.7
(-1.9)
P 		3735.5
(-2.7)
P 		3518.8
(-3)
P 		8334
(3)
P 		4815
avr 6121.7
(0.8) 		4467.9
(-1.9) 		4649.5
(-1.6) 		3951.6
(-2.8) 		3803.4
(-3) 		7419.1
(3) 		3616
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2670
1 2 3 4 range
A 1122.2
(-3)
P 		1179.1
(-2.8)
P 		2204.3
(1.7)
P 		2514.4
(3)
P 		1392
B 1005.3
(-3)
P 		1363.2
(-2.2)
P 		1829.4
(-1.1)
P 		3674.8
(3)
P 		2670
C 1110.1
(-3)
P 		1412.8
(-1.9)
P 		2690.2
(2.5)
P 		2826.1
(3)
P 		1716
avr 1079.2
(-3) 		1318.4
(-2.3) 		2241.3
(0.6) 		3005.1
(3) 		1926

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2039
1 2 3 4 5 6 range
A 1156.5
(-1.2)
P 		1531.7
(1.6)
P 		1048.9
(-2.1)
P 		924.5
(-3)
P 		1087.2
(-1.8)
P 		1711.7
(3)
P 		787
B 2257.9
(1.7)
P 		1507.7
(-1.5)
P 		1148
(-3)
P 		1185.1
(-2.8)
P 		1742.3
(-0.5)
P 		2570.2
(3)
P 		1422
C 2076.6
(0.9)
P 		1393.6
(-1.1)
P 		1121.1
(-1.9)
P 		751.2
(-3)
P 		1138.6
(-1.9)
P 		2789.9
(3)
P 		2039
avr 1830.3
(0.7) 		1477.7
(-0.8) 		1106
(-2.3) 		953.6
(-3) 		1322.7
(-1.4) 		2357.3
(3) 		1404
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173472_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23230
Sequence Type Exemplar sequence
Representative Public ID 2190266 NCBI
Target Description g2190266 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=Y57A10C.6 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=Y57A10C.6 /WP=CE18418 /CHR=2 /FEA=Genomic Cluster /DEF=3-keto-acyl-CoA thiolase
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064238(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064238 NCBI Caenorhabditis elegans Y57A10C.6 (Y57A10C.6) mRNA, complete cds. 11/11 None
SNAP00000005456 ENSEMBL cdna:SNAP chromosome:CEL140:II:12423511:12425593:-1 11/11 None
GENEFINDER00000005460 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12421054:12425593:-1 10/11 None
Y57A10C.6 ENSEMBL cdna:known chromosome:CEL140:II:12423417:12425597:-1 gene:Y57A10C.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12423485-12425591(-) 100.0 100.0
Public Domain and Genome References
Gene Title 3-keto-acyl-CoA thiolase
Ensembl Y57A10C.6
Entrez Gene 174881 Entrez gene
SwissProt O02353 EMBL-EBI
WormBase CE18418 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1602493_S_AT similar to podocan cfa
CANINE:1589982_S_AT similar to podocan cfa
CANINE_2:CFA.17838.1.S1_S_AT similar to podocan cfa
CANINE_2:CFA.20912.1.S1_S_AT similar to podocan cfa
CANINE_2:CFAAFFX.29274.1.S1_AT similar to podocan cfa
CANINE_2:CFAAFFX.29299.1.S1_S_AT similar to podocan cfa
CANINE_2:CFAAFFX.29303.1.S1_S_AT similar to podocan cfa
DROSOPHILA_2:1630643_AT Sterol carrier protein X-related thiolase dm
DROSOPHILA_2:1628744_S_AT Sterol carrier protein X-related thiolase dm
DROSGENOME1:153713_AT Sterol carrier protein X-related thiolase dm
DROSGENOME1:141671_S_AT Sterol carrier protein X-related thiolase dm
HG-FOCUS:201339_S_AT sterol carrier protein 2 hs
HG-U133A:201339_S_AT sterol carrier protein 2 hs
HG-U133_PLUS_2:201339_S_AT sterol carrier protein 2 hs
HG-U133A_2:201339_S_AT sterol carrier protein 2 hs
HG-U133_PLUS_2:211733_X_AT sterol carrier protein 2 hs
HG-U133A:211733_X_AT sterol carrier protein 2 hs
HG-U133A_2:211733_X_AT sterol carrier protein 2 hs
HU35KSUBC:RC_AA084631_AT sterol carrier protein 2 hs
HUGENEFL:U11313_AT sterol carrier protein 2 hs
U133_X3P:G4506822_3P_S_AT sterol carrier protein 2 hs
U133_X3P:G13543502_3P_AT sterol carrier protein 2 hs
HG-U95AV2:36688_AT sterol carrier protein 2 hs
HG-U95B:59385_AT sterol carrier protein 2 hs
HG-U95D:90029_AT sterol carrier protein 2 hs
HU35KSUBD:RC_AA204876_AT Sterol carrier protein 2 hs
U133_X3P:HS.206097.0.S2_3P_AT Sterol carrier protein 2 hs
HG-U133A_2:212589_AT Sterol carrier protein 2 hs
HG-FOCUS:212589_AT Sterol carrier protein 2 hs
HG-U133_PLUS_2:212589_AT Sterol carrier protein 2 hs
HG-U133A:212589_AT Sterol carrier protein 2 hs
HG-U95AV2:32827_AT Sterol carrier protein 2 hs
MOUSE430_2:1449686_S_AT sterol carrier protein 2, liver mm
MOE430A:1449686_S_AT sterol carrier protein 2, liver mm
MOUSE430A_2:1449686_S_AT sterol carrier protein 2, liver mm
MOE430A:1426219_AT sterol carrier protein 2, liver mm
MOUSE430_2:1426219_AT sterol carrier protein 2, liver mm
MOUSE430A_2:1426219_AT sterol carrier protein 2, liver mm
MU11KSUBA:M91458_S_AT sterol carrier protein 2, liver mm
MG-U74AV2:95787_S_AT sterol carrier protein 2, liver mm
MG-U74AV2:93278_AT sterol carrier protein 2, liver mm
MOE430A:1419974_AT sterol carrier protein 2, liver mm
MOUSE430A_2:1419974_AT sterol carrier protein 2, liver mm
MOUSE430_2:1419974_AT sterol carrier protein 2, liver mm
RG-U34A:M58287_S_AT sterol carrier protein 2 rn
RG-U34A:M62763COMPLETE_SEQ_AT sterol carrier protein 2 rn
RAE230A:1370296_AT sterol carrier protein 2 rn
RAT230_2:1370296_AT sterol carrier protein 2 rn
RAE230A:1387896_AT sterol carrier protein 2 rn
RAT230_2:1387896_AT sterol carrier protein 2 rn
RG-U34B:RC_AA956828_AT Sterol carrier protein 2 rn
RG-U34B:RC_AI058987_AT Sterol carrier protein 2 rn
Protein Similarities
Method ID Description E-Value
blast CAA19548 Hypothetical protein Y57A10C.6 [Caenorhabditis elegans] ref|NP_496639.1| Y57A10C.6 [Caenorhabditis elegans] dbj|BAA20377.1| 3-keto-acyl-CoA thiolase [Caenorhabditis elegans] 0.0
blast CAE73507 Hypothetical protein CBG20965 [Caenorhabditis briggsae] 0.0
blast NP_001029162 sterol carrier protein 2 [Bos taurus] gb|AAI03371.1| Unknown (protein for MGC:127405) [Bos taurus] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR002155 EMBL-EBI Thiolase 2.7E-25
Pfam IPR002155 EMBL-EBI Thiolase 1.4E-34
Pfam IPR002155 EMBL-EBI Thiolase 1.1E-35
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 2.1E-50
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000005460 3 435-457,461-483,524-546
Sequence
Target Sequence 
>C. ELEGANS:173472_S_AT
ctacgactttatgggtctcctcgagtgcagtccaacatccgacggagccgccgcagccgt
cctggtctccgagaaatttttggagaagaatccaagactgaaagcccaggccgtggagat
tgtgggcctaaagctgggaaccgatgagccatccgtgttcgctgagaattcaaatatcaa
aatgattggattcgatatgattcaaaagttggccaagcaactgtgggccgagacaaagct
tactccaaatgatgtccaggtcattgagcttcacgattgctttgctccaaatgagctcat
tacctatgaagccatcgggctctgcccagtaggtcaaggacatcatatcgtagatcgaaa
tgataatacatatggcgggaaatgggtgatcaatccatccggaggcttgatctcgaaggg
acatcctatcggagcaaccggtgtggctcaagctgtcgagctgtccaaccagctacgtgg
caaatgtggaaagagacaagtgccgaactgcaaagtcgccatgcaacataatattggaat
tggtggagctggagtagttgggctctatagattgggattccctggagctgcac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTACGACTTTATGGGTCTCCTCGAG 290 225 646 Antisense
GAAAGCCCAGGCCGTGGAGATTGTG 103 359 745 Antisense
GTGGGCCTAAAGCTGGGAACCGATG 604 485 767 Antisense
AGCCATCCGTGTTCGCTGAGAATTC 164 85 792 Antisense
GATGTCCAGGTCATTGAGCTTCACG 475 407 896 Antisense
GCTCTGCCCAGTAGGTCAAGGACAT 646 299 964 Antisense
CAATCCATCCGGAGGCTTGATCTCG 425 181 1036 Antisense
GAAGGGACATCCTATCGGAGCAACC 619 333 1060 Antisense
GTGGCTCAAGCTGTCGAGCTGTCCA 683 491 1088 Antisense
CTGTCCAACCAGCTACGTGGCAAAT 7 241 1106 Antisense
AGATTGGGATTCCCTGGAGCTGCAC 689 63 1214 Antisense
Sequence Source GenBank