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[173465_at]

Description g1245047 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=Y39H10A.7 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=Y39H10A.7 /WP=CE26076 /CHR=5 /FEA=Genomic Cluster /GEN=chk1 /DEF=serine-threonine kinase
Cluster 6grp_high1_10_10 > 89      4grp_high_8_8 > 52      6grp_total > 99      4grp_total > 59      6grp_cgc > 79      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 110.6
(-2.2)
P 		132.4
(0.4)
P 		154.1
(3)
P 		103.7
(-3)
A 		50
B 133.6
(0.6)
P 		167.4
(3)
P 		163.9
(2.8)
P 		82.6
(-3)
P 		85
C 127.1
(3)
P 		125
(2.6)
P 		92.4
(-3)
P 		106.9
(-0.5)
P 		35
avr 123.8
(0.6) 		141.6
(3) 		136.8
(2.3) 		97.7
(-3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 133
1 2 3 4 5 6 range
A 107.4
(-0.1)
P 		95
(-0.9)
P 		80.1
(-1.9)
P 		62.4
(-3)
P 		155.9
(3)
P 		139.8
(2)
P 		94
B 72
(-2.4)
P 		106.4
(-0.9)
P 		75.8
(-2.3)
P 		59.9
(-3)
P 		158.2
(1.5)
P 		191.3
(3)
P 		131
C 125.5
(0.6)
P 		58.4
(-3)
P 		73.7
(-2.2)
P 		97.9
(-0.9)
A 		158.1
(2.4)
P 		169.1
(3)
P 		111
avr 101.6
(-1.2) 		86.6
(-2.2) 		76.5
(-2.8) 		73.4
(-3) 		157.4
(2.4) 		166.7
(3) 		93
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 27
1 2 3 4 range
A 40.3
(3)
P 		28.7
(0.2)
P 		40.3
(3)
P 		15.2
(-3)
A 		25
B 42.6
(3)
P 		41.3
(2.7)
P 		38
(1.9)
P 		17.6
(-3)
P 		25
C 42.1
(3)
P 		35.9
(1.5)
P 		32.2
(0.5)
P 		18
(-3)
P 		24
avr 41.7
(3) 		35.3
(1.5) 		36.8
(1.8) 		16.9
(-3) 		25

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 19.8
(-2.2)
P 		33.8
(0.5)
P 		17.4
(-2.7)
P 		15.8
(-3)
P 		47
(3)
P 		34
(0.5)
P 		31
B 25.1
(-2)
P 		35.4
(-0.9)
P 		18.4
(-2.7)
P 		15.9
(-3)
P 		64.3
(2.2)
P 		71.3
(3)
P 		55
C 46.5
(1.4)
P 		17.8
(-3)
P 		18.7
(-2.9)
P 		19.7
(-2.7)
A 		51.1
(2.1)
P 		56.6
(3)
P 		39
avr 30.5
(-0.8) 		29
(-1.1) 		18.2
(-2.8) 		17.1
(-3) 		54.1
(3) 		54
(3) 		37
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173465_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25727
Sequence Type Exemplar sequence
Representative Public ID 1245047 NCBI
Target Description g1245047 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=Y39H10A.7 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=Y39H10A.7 /WP=CE26076 /CHR=5 /FEA=Genomic Cluster /GEN=chk1 /DEF=serine-threonine kinase
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029062(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029062 NCBI Caenorhabditis elegans CHeckpoint Kinase family member (chk-1) (chk-1) mRNA, complete cds. 11/11 None
Y39H10A.7a ENSEMBL cdna:known chromosome:CEL140:V:3756825:3759283:-1 gene:Y39H10A.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_001029063 7/11 Cross Hyb Matching Probes None
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
3565921 2 1 NM_001029062 173465_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:3756835-3759278(-) 100.0 100.0
Public Domain and Genome References
Ensembl Y39H10A.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAF59485 Checkpoint kinase protein 1, isoform a [Caenorhabditis elegans] ref|NP_001024233.1| CHeckpoint Kinase family member (chk-1) [Caenorhabditis elegans] sp|Q9N3Z3|CHK1_CAEEL Serine/threonine-protein kinase chk-1 0.0
blast AAP13756 Checkpoint kinase protein 1, isoform b [Caenorhabditis elegans] ref|NP_001024234.1| CHeckpoint Kinase family member (chk-1) [Caenorhabditis elegans] 0.0
blast AAA93318 serine/threonine kinase 0.0
Protein Families
Method ID Description E-Value
hanks 2.2.12 CaMK Group; CaMK II KIN1/SNF1/Nim1; YCL24 2.0E-62
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 4.6E-72
Sequence
Target Sequence 
>C. ELEGANS:173465_AT
atgtggatgtctaattgtttttttttgtttgttcgttttttgttccatcagactattgag
atttaaagcacaatatttatcatcatcatcatcactttaaacatctccctatcccattaa
tttttaaatttaacgtgaattaacgccgaattacaagcctgtgaatgaatgtttgttttt
atctctgcgtctagagtttgtccccactgcctcatcattcctcctctttctcttttccct
ctctcacttttgcacaatatctcgctgccc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGTGGATGTCTAATTGTTTTTTTT 692 49 1512 Antisense
TTTTTTGTTCCATCAGACTATTGAG 313 675 1547 Antisense
AAAGCACAATATTTATCATCATCAT 698 123 1576 Antisense
ATCATCACTTTAAACATCTCCCTAT 629 29 1599 Antisense
TAACGTGAATTAACGCCGAATTACA 154 637 1642 Antisense
TTAACGCCGAATTACAAGCCTGTGA 534 659 1651 Antisense
AAGCCTGTGAATGAATGTTTGTTTT 7 149 1666 Antisense
AATGTTTGTTTTTATCTCTGCGTCT 37 165 1679 Antisense
TCTCTGCGTCTAGAGTTTGTCCCCA 307 611 1693 Antisense
CCTCTCTCACTTTTGCACAATATCT 31 269 1749 Antisense
ACTTTTGCACAATATCTCGCTGCCC 272 103 1757 Antisense
Sequence Source GenBank