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[173456_at]

Description g1943752 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=C02H7.3 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=C02H7.3 /WP=CE16806 /CHR=X /FEA=Genomic Cluster /GEN=aex-3 /DEF=regulator of presynaptic activity
Cluster 6grp_highest_10_10 > 61      6grp_high1_10_10 > 27      4grp_highest_8_8 > 61      4grp_high_8_8 > 17      6grp_highest_nonorm > 90      6grp_total > 27      4grp_total > 30      6grp_highest_sub > De      6grp_cgc > 13      6grp_high1_sub > Cu      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 236
1 2 3 4 range
A 304.4
(3)
P 		103.7
(-2.2)
P 		70.6
(-3)
P 		199.8
(0.3)
P 		234
B 279
(3)
P 		68.8
(-3)
P 		75.2
(-2.8)
P 		141.8
(-0.9)
P 		210
C 207.2
(3)
P 		164.1
(0.8)
P 		88.8
(-3)
P 		185.3
(1.9)
P 		118
avr 263.5
(3) 		112.2
(-1.9) 		78.2
(-3) 		175.6
(0.2) 		185

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 175
1 2 3 4 5 6 range
A 260.1
(3)
P 		133.4
(-1.4)
P 		129.3
(-1.5)
P 		85.4
(-3)
P 		102.1
(-2.4)
P 		119.8
(-1.8)
P 		175
B 189.3
(3)
P 		189.9
(3)
P 		106
(-2.1)
P 		91.7
(-3)
P 		110.1
(-1.9)
P 		138.3
(-0.2)
P 		98
C 239.1
(3)
P 		174.7
(0.5)
P 		86
(-3)
P 		93.3
(-2.7)
P 		104.6
(-2.3)
P 		109.4
(-2.1)
P 		153
avr 229.5
(3) 		166
(0.3) 		107.1
(-2.3) 		90.1
(-3) 		105.6
(-2.3) 		122.5
(-1.6) 		139
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 94
1 2 3 4 range
A 110.8
(3)
P 		22.5
(-2.7)
P 		18.4
(-3)
P 		29.3
(-2.3)
P 		92
B 89
(3)
P 		17
(-3)
P 		17.4
(-3)
P 		30.2
(-1.9)
P 		72
C 68.6
(3)
P 		47.2
(-0.4)
P 		30.9
(-3)
P 		31.2
(-3)
P 		38
avr 89.5
(3) 		28.9
(-2.4) 		22.2
(-3) 		30.2
(-2.3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 70
1 2 3 4 5 6 range
A 47.9
(3)
P 		47.4
(2.9)
P 		28.2
(-1.5)
P 		21.7
(-3)
P 		30.8
(-0.9)
P 		29.2
(-1.3)
P 		26
B 65.9
(3)
P 		63.2
(2.6)
P 		25.8
(-2.8)
P 		24.3
(-3)
P 		44.8
(-0)
P 		51.6
(0.9)
P 		42
C 88.6
(3)
P 		53.3
(-0)
P 		21.9
(-2.7)
P 		18.8
(-3)
P 		33.9
(-1.7)
P 		36.6
(-1.5)
P 		70
avr 67.5
(3) 		54.6
(1.3) 		25.3
(-2.5) 		21.6
(-3) 		36.5
(-1.1) 		39.1
(-0.7) 		46
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173456_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.26154
Sequence Type Exemplar sequence
Representative Public ID 1943752 NCBI
Target Description g1943752 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=C02H7.3 /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=C02H7.3 /WP=CE16806 /CHR=X /FEA=Genomic Cluster /GEN=aex-3 /DEF=regulator of presynaptic activity
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171618(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171618 NCBI Caenorhabditis elegans Aboc, EXpulsion defective family member (aex-3) (aex-3) mRNA, complete cds. 11/11 A 
C02H7.3a ENSEMBL cdna:known chromosome:CEL140:X:751201:759731:-1 gene:C02H7.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
180420 2 1 NM_171618 173456_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:751220-759701(-) 100.0 100.0
Public Domain and Genome References
Ensembl C02H7.3
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAC47926 Aboc, expulsion defective protein 3, isoform a [Caenorhabditis elegans] ref|NP_741710.1| Aboc, EXpulsion defective family member (aex-3) [Caenorhabditis elegans] gb|AAB52421.1| regulator of presynaptic activity [Caenorhabditis elegans] sp|O02626|AEX3_CAEEL Regulator of presynaptic activity aex-3 0.0
blast AAM51509 Aboc, expulsion defective protein 3, isoform b [Caenorhabditis elegans] ref|NP_001024342.1| Aboc, EXpulsion defective family member (aex-3) [Caenorhabditis elegans] 0.0
blast CAE63627 Hypothetical protein CBG08121 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005112 EMBL-EBI dDENN domain 2.2E-29
Pfam IPR001194 EMBL-EBI DENN (AEX-3) domain 1.4E-102
Pfam IPR005113 EMBL-EBI uDENN domain 3.8E-48
Sequence
Target Sequence 
>C. ELEGANS:173456_AT
tctttttattcttgttttcctcgatttcttagaaatgtagatatttgaattttaattaat
ttatacagatacacataacataatataaaacactcacatttgactttatgacagtgcaat
tttagtcatgttctttcttctttttccttttttgtcgttttctccgtttttttttgcttg
acttgctttgagtttacattctatccaggccaacttcttttgtcttcatttcgtttcttc
tcaaaattgtcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTTTTTATTCTTGTTTTCCTCGAT 433 615 4257 Antisense
TTCTTGTTTTCCTCGATTTCTTAGA 37 689 4265 Antisense
AAACACTCACATTTGACTTTATGAC 441 129 4344 Antisense
GACAGTGCAATTTTAGTCATGTTCT 347 369 4366 Antisense
TTAGTCATGTTCTTTCTTCTTTTTC 473 681 4378 Antisense
TCTCCGTTTTTTTTTGCTTGACTTG 337 611 4417 Antisense
TTTGCTTGACTTGCTTTGAGTTTAC 62 669 4429 Antisense
TTGAGTTTACATTCTATCCAGGCCA 612 705 4444 Antisense
TTACATTCTATCCAGGCCAACTTCT 351 683 4450 Antisense
CCAACTTCTTTTGTCTTCATTTCGT 184 273 4466 Antisense
TTTCGTTTCTTCTCAAAATTGTCAT 162 657 4485 Antisense
Sequence Source GenBank