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[173431_at]

Description g451656-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g451656 /5_PRIME_EXT_DB=GenBank Identifier /CHR=5 /FEA=Genomic Cluster /GEN=pc2 /DEF=prohormone convertase 2
Cluster 6grp_highest_10_10 > 50      6grp_high1_10_10 > 16      4grp_highest_8_8 > 46      4grp_high_8_8 > 11      6grp_highest_nonorm > 05      6grp_total > 06      4grp_total > 21      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10347
1 2 3 4 range
A 10141.4
(1.5)
P 		5314.2
(-1.7)
P 		3364.5
(-3)
P 		12371.9
(3)
P 		9007
B 10054.2
(1.8)
P 		4927.5
(-2)
P 		3622
(-3)
P 		11666.7
(3)
P 		8045
C 10243.8
(1.1)
P 		5031.3
(-1.9)
P 		3194.3
(-3)
P 		13541.4
(3)
P 		10347
avr 10146.5
(1.4) 		5091
(-1.9) 		3393.6
(-3) 		12526.7
(3) 		9133

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6279
1 2 3 4 5 6 range
A 11260.8
(3)
P 		7802.9
(-0.6)
P 		7152.4
(-1.3)
P 		5542.4
(-3)
P 		6178.9
(-2.3)
P 		6664.1
(-1.8)
P 		5718
B 10273.6
(3)
P 		8258.9
(0.5)
P 		5931.3
(-2.3)
P 		7175.5
(-0.8)
P 		5360.7
(-3)
P 		5464.7
(-2.9)
P 		4913
C 8719.6
(3)
P 		8270.5
(2.3)
P 		6780
(-0.1)
P 		5938
(-1.5)
P 		5660.6
(-1.9)
P 		4981.9
(-3)
P 		3738
avr 10084.7
(3) 		8110.8
(0.3) 		6621.2
(-1.7) 		6218.6
(-2.3) 		5733.4
(-3) 		5703.6
(-3) 		4381
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2853
1 2 3 4 range
A 3692.5
(3)
P 		1153.6
(-2.4)
P 		879.5
(-3)
P 		1811
(-1)
P 		2813
B 3206.2
(3)
P 		1217
(-2)
P 		839.3
(-3)
P 		2486.2
(1.2)
P 		2367
C 3391
(3)
P 		1446.5
(-2.1)
P 		1113.3
(-3)
P 		2283.3
(0.1)
P 		2278
avr 3429.9
(3) 		1272.4
(-2.2) 		944
(-3) 		2193.5
(0) 		2486

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2381
1 2 3 4 5 6 range
A 2075.8
(-0.1)
P 		2775.1
(3)
P 		1557.7
(-2.3)
P 		1405.7
(-3)
P 		1864.5
(-1)
P 		1622.5
(-2.1)
P 		1369
B 3574.7
(3)
P 		2749.1
(0.7)
P 		1440.3
(-3)
P 		1900.5
(-1.7)
P 		2178
(-0.9)
P 		2037.8
(-1.3)
P 		2134
C 3232
(3)
P 		2523.6
(0.9)
P 		1725.6
(-1.4)
P 		1194.1
(-3)
P 		1831.7
(-1.1)
P 		1667.7
(-1.6)
P 		2038
avr 2960.8
(3) 		2682.6
(1.9) 		1574.5
(-2.7) 		1500.1
(-3) 		1958.1
(-1.1) 		1776
(-1.9) 		1461
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173431_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.25136
Sequence Type Exemplar sequence
Representative Public ID 451656 NCBI
Target Description g451656-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g451656 /5_PRIME_EXT_DB=GenBank Identifier /CHR=5 /FEA=Genomic Cluster /GEN=pc2 /DEF=prohormone convertase 2
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028561(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028561 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-3) (egl-3) mRNA, complete cds. 11/11 None
C51E3.7b.1 ENSEMBL cdna:known chromosome:CEL140:V:10171777:10176335:-1 gene:C51E3.7 11/11 A 
C51E3.7a.3 ENSEMBL cdna:known chromosome:CEL140:V:10171839:10176335:-1 gene:C51E3.7 11/11 None
C51E3.7a.1 ENSEMBL cdna:known chromosome:CEL140:V:10171839:10176333:-1 gene:C51E3.7 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_073213 7/11 Cross Hyb Matching Probes A 
C51E3.7b.2 7/11 Cross Hyb Matching Probes A 
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
179412 2 1 NM_001028561 173431_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:10171791-10176336(-) 100.0 100.0
Public Domain and Genome References
Ensembl C51E3.7
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB01635 Hypothetical protein C51E3.7a [Caenorhabditis elegans] ref|NP_001023732.1| EGg Laying defective family member (egl-3) [Caenorhabditis elegans] gb|AAA56868.1| prohormone convertase 2 [Caenorhabditis elegans] 0.0
blast ABA29807 convertase 2 precursor [Brugia malayi] 0.0
blast AAK66762 proprotein convertase 2 [Heterodera glycines] 0.0
blast CAB01642 Hypothetical protein C51E3.7b [Caenorhabditis elegans] ref|NP_505614.3| EGg Laying defective family member (egl-3) [Caenorhabditis elegans] 0.0
blast CAE64748 Hypothetical protein CBG09536 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 2.9E-76
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.5E-88
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 2.9E-76
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.6E-109
Sequence
Target Sequence 
>C. ELEGANS:173431_AT
aaacgcagccactaaatgtacaaaattccccaatttcttccttccttcaaaaaatttcta
agaatttcctcttcctcctcctctttttaactagttgaaaatgaaacagatcatcgagct
tcccagtcgacccgcccccaatatccggtgatccgtattgttgtagtcgcttcgggtgcc
gcacacagatttacagatttttatattttgtaagtatattccatcaaatcgtccatcacc
accattcgccccacccatttcttcttttttctatttctccctcttcctttttttctctcc
ccttcatatttttattgtcagtttttcgacccgatcatcacatcacaattgttaaatgag
ctgagccacacacacacaaacacaaatgacagacacaaaacatcattaccatctgaaacg
aaaaccgaaaagagcccttaaaatctctctcactccatcatcacaccatcttcattcgcc
atgcaaatccctgcgcgcacaagtcgaaccacccataataaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACGCAGCCACTAAATGTACAAAA 211 125 1962 Antisense
TGAAACAGATCATCGAGCTTCCCAG 464 573 2063 Antisense
AATATCCGGTGATCCGTATTGTTGT 487 173 2101 Antisense
TATTGTTGTAGTCGCTTCGGGTGCC 349 663 2117 Antisense
GGTGCCGCACACAGATTTACAGATT 353 501 2136 Antisense
TATATTCCATCAAATCGTCCATCAC 237 661 2176 Antisense
TTTTTCGACCCGATCATCACATCAC 164 675 2283 Antisense
AAATGAGCTGAGCCACACACACACA 415 117 2315 Antisense
AGAGCCCTTAAAATCTCTCTCACTC 647 69 2392 Antisense
CATCTTCATTCGCCATGCAAATCCC 267 213 2428 Antisense
CACAAGTCGAACCACCCATAATAAA 649 187 2459 Antisense
Sequence Source GenBank