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[173429_at]

Description g5731969-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g5731969 /5_PRIME_EXT_DB=GenBank Identifier /CHR=X /FEA=Genomic Cluster /GEN=cdk-4 /DEF=cyclin-dependent kinase CDK-4
Cluster 6grp_high1_10_10 > 36      6grp_total > 35      4grp_total > 61      6grp_cgc > 34      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 180
1 2 3 4 range
A 187.2
(3)
P 		166.8
(2.3)
M 		117.1
(0.7)
P 		7.1
(-3)
A 		180
B 167.6
(3)
P 		103.7
(-0.3)
P 		140.1
(1.6)
P 		50.2
(-3)
M 		117
C 118.4
(-0.1)
P 		157.8
(3)
P 		110.8
(-0.7)
P 		82
(-3)
M 		76
avr 157.7
(3) 		142.8
(2.2) 		122.7
(1.1) 		46.4
(-3) 		111

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 116
1 2 3 4 5 6 range
A 69.2
(-2.5)
A 		81
(-1.4)
P 		126.7
(3)
P 		64
(-3)
P 		71.1
(-2.3)
P 		68
(-2.6)
P 		63
B 149.2
(1.8)
P 		172.2
(3)
P 		121.2
(0.4)
M 		57.4
(-3)
A 		56.7
(-3)
P 		116
(0.1)
P 		116
C 165.9
(3)
P 		150
(1.9)
P 		116.1
(-0.5)
P 		90.6
(-2.3)
A 		80.1
(-3)
P 		113.7
(-0.7)
P 		86
avr 128.1
(2.4) 		134.4
(3) 		121.3
(1.8) 		70.7
(-2.9) 		69.3
(-3) 		99.2
(-0.2) 		65
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 68.2
(3)
P 		36.2
(0.1)
M 		30.6
(-0.4)
P 		1
(-3)
A 		67
B 53.4
(3)
P 		25.6
(-0.9)
P 		32.5
(0.1)
P 		10.7
(-3)
M 		43
C 39.2
(1.8)
P 		45.4
(3)
P 		38.6
(1.7)
P 		13.8
(-3)
M 		32
avr 53.6
(3) 		35.7
(0.6) 		33.9
(0.4) 		8.5
(-3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 12.8
(-3)
A 		28.8
(3)
P 		27.6
(2.6)
P 		16.2
(-1.7)
P 		21.5
(0.3)
P 		16.6
(-1.6)
P 		16
B 51.9
(2.2)
P 		57.3
(3)
P 		29.4
(-1)
M 		15.2
(-3)
A 		23
(-1.9)
P 		43.3
(1)
P 		42
C 61.5
(3)
P 		45.8
(0.8)
P 		29.6
(-1.4)
P 		18.2
(-3)
A 		25.9
(-1.9)
P 		38
(-0.3)
P 		43
avr 42.1
(2.6) 		44
(3) 		28.9
(-0.3) 		16.5
(-3) 		23.5
(-1.5) 		32.6
(0.5) 		28
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173429_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.26037
Sequence Type Exemplar sequence
Representative Public ID 5731969 NCBI
Target Description g5731969-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g5731969 /5_PRIME_EXT_DB=GenBank Identifier /CHR=X /FEA=Genomic Cluster /GEN=cdk-4 /DEF=cyclin-dependent kinase CDK-4
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077855(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077855 NCBI Caenorhabditis elegans Cyclin-Dependent Kinase family member (cdk-4) (cdk-4) mRNA, complete cds. 11/11 A 
F18H3.5a ENSEMBL cdna:known chromosome:CEL140:X:13515773:13518823:-1 gene:F18H3.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
181472 2 1 NM_077855 173429_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13515772-13518824(-) 100.0 100.0
Public Domain and Genome References
Ensembl F18H3.5
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA90447 Hypothetical protein F18H3.5a [Caenorhabditis elegans] emb|CAB16925.1| Hypothetical protein F18H3.5a [Caenorhabditis elegans] ref|NP_510256.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] gb|AAD48898.1| cyclin-dependent kinase CDK-4 [Caenorhabditis elegans] 0.0
blast CAB16923 Hypothetical protein F18H3.5b [Caenorhabditis elegans] ref|NP_001024591.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] 1.0E-172
blast AAM78549 cyclin-dependent kinase CDK-4/6 [Caenorhabditis briggsae] emb|CAE63134.1| Hypothetical protein CBG07433 [Caenorhabditis briggsae] 1.0E-127
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-70
hanks 3.1.4 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk4 7.0E-80
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.9E-88
Sequence
Target Sequence 
>C. ELEGANS:173429_AT
gtgaaaccagatattcatttttttttgtatttttccattttgacttattcattttttttt
tcaatgttatgacactttctccacgtgtatatatctttgtgtgctgctgcgctgttttat
ttttagtgtgatctcttaaatgttgtgaattcctgacaatgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGAAACCAGATATTCATTTTTTTT 370 481 1039 Antisense
GTATTTTTCCATTTTGACTTATTCA 298 453 1065 Antisense
TTCCATTTTGACTTATTCATTTTTT 374 699 1071 Antisense
CAATGTTATGACACTTTCTCCACGT 233 183 1100 Antisense
GTTATGACACTTTCTCCACGTGTAT 502 447 1104 Antisense
ACTTTCTCCACGTGTATATATCTTT 212 103 1112 Antisense
GTATATATCTTTGTGTGCTGCTGCG 279 453 1125 Antisense
TGCTGCTGCGCTGTTTTATTTTTAG 248 583 1140 Antisense
GCTGTTTTATTTTTAGTGTGATCTC 607 295 1149 Antisense
GTGTGATCTCTTAAATGTTGTGAAT 38 489 1164 Antisense
AATGTTGTGAATTCCTGACAATGAT 180 165 1177 Antisense
Sequence Source GenBank