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[173423_at]

Description g8037936-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g8037936 /5_PRIME_EXT_DB=GenBank Identifier /CHR=4 /FEA=Genomic Cluster /GEN=unc-43 /DEF=calcium-calmodulin-dependent protein kinase IIisoform H
Cluster 4grp_high_8_8 > 18      6grp_total > 28      4grp_total > 30      6grp_cgc > 06      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 85.3
(3)
P 		46.6
(-3)
P 		47.1
(-2.9)
P 		53.3
(-2)
A 		39
B 72.7
(1.1)
P 		40.3
(-3)
A 		43
(-2.7)
M 		87.6
(3)
P 		47
C 89.2
(3)
P 		81.5
(1.7)
P 		52.6
(-3)
P 		73
(0.3)
P 		37
avr 82.4
(3) 		56.1
(-1.5) 		47.6
(-3) 		71.3
(1.1) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 102
1 2 3 4 5 6 range
A 116
(3)
P 		39.3
(-1.6)
A 		17.3
(-2.9)
A 		29
(-2.2)
A 		24.5
(-2.5)
P 		16.2
(-3)
A 		100
B 64.2
(3)
P 		39.6
(-0.9)
P 		31.9
(-2.1)
A 		26.4
(-3)
A 		51.4
(1)
P 		49.4
(0.7)
P 		38
C 78.8
(3)
P 		39.8
(-0.6)
A 		26.4
(-1.9)
A 		14.3
(-3)
A 		31.2
(-1.4)
A 		58.9
(1.1)
P 		65
avr 86.3
(3) 		39.6
(-1.4) 		25.2
(-2.8) 		23.2
(-3) 		35.7
(-1.8) 		41.5
(-1.3) 		63
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 31.1
(3)
P 		10.1
(-2.4)
P 		12.3
(-1.8)
P 		7.8
(-3)
A 		23
B 23.2
(3)
P 		9.9
(-3)
A 		10
(-3)
M 		18.7
(1)
P 		13
C 29.5
(3)
P 		23.4
(0.9)
P 		18.3
(-0.9)
P 		12.3
(-3)
P 		17
avr 27.9
(3) 		14.5
(-2.4) 		13.5
(-2.8) 		12.9
(-3) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 21.4
(3)
P 		14
(0.5)
A 		3.8
(-3)
A 		7.4
(-1.8)
A 		7.4
(-1.8)
P 		3.9
(-3)
A 		18
B 22.3
(3)
P 		13.2
(-0.6)
P 		7.8
(-2.7)
A 		7
(-3)
A 		20.9
(2.5)
P 		18.4
(1.5)
P 		15
C 29.2
(3)
P 		12.1
(-0.9)
A 		6.7
(-2.1)
A 		2.9
(-3)
A 		10.1
(-1.4)
A 		19.7
(0.8)
P 		26
avr 24.3
(3) 		13.1
(-0.6) 		6.1
(-2.9) 		5.8
(-3) 		12.8
(-0.7) 		14
(-0.3) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173423_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24679
Sequence Type Exemplar sequence
Representative Public ID 8037936 NCBI
Target Description g8037936-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g8037936 /5_PRIME_EXT_DB=GenBank Identifier /CHR=4 /FEA=Genomic Cluster /GEN=unc-43 /DEF=calcium-calmodulin-dependent protein kinase IIisoform H
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028130(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028130 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
K11E8.1i ENSEMBL cdna:known chromosome:CEL140:IV:10328371:10340140:-1 gene:K11E8.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
177921 12 1 NM_001028122 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028123 187759_s_at (11), 193459_s_at (11)
NM_001028124 172058_x_at (9), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028125 172058_x_at (11), 175821_s_at (11), 175824_s_at (11), 187759_s_at (11), 193459_s_at (11)
NM_001028126 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11)
NM_001028127 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028128 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028129 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028130 172058_x_at (11), 173423_at (11), 193459_s_at (11)
NM_001028131 175821_s_at (11), 175824_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028132 172058_x_at (9), 175821_s_at (11), 175824_s_at (11), 193459_s_at (11)
NM_001028133 175821_s_at (11), 193463_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10328799-10340147(-) 97.65 100.0
Public Domain and Genome References
Ensembl K11E8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAC42322 Hypothetical protein K11E8.1i [Caenorhabditis elegans] emb|CAC42360.1| Hypothetical protein K11E8.1i [Caenorhabditis elegans] ref|NP_001023301.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF71543.1| calcium/calmodulin-dependent protein kinase II isoform H; CaMKIIH [Caenorhabditis elegans] 0.0
blast CAC42323 Hypothetical protein K11E8.1g [Caenorhabditis elegans] emb|CAC42361.1| Hypothetical protein K11E8.1g [Caenorhabditis elegans] ref|NP_001023299.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63320.1| calcium/calmodulin-dependent protein kinase II isoform B [Caenorhabditis elegans] 0.0
blast CAC42326 Hypothetical protein K11E8.1d [Caenorhabditis elegans] emb|CAC42364.1| Hypothetical protein K11E8.1d [Caenorhabditis elegans] ref|NP_001023296.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAD53949.1| calcium/calmodulin dependent protein kinase II [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-66
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-138
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-97
Sequence
Target Sequence 
>C. ELEGANS:173423_AT
ggtaacgagtgattccaaacatttttaagttttgctctatctttctttctttctttatct
ctttctcttccttatatttatacatctaatagttagatattcacatcttgtttatcatca
gaaacaacactatttatacccaattagataatacccagggatcgagaagatccggaagat
ccgcttgctttca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTAACGAGTGATTCCAAACATTTT 633 503 1055 Antisense
GAGTGATTCCAAACATTTTTAAGTT 436 401 1061 Antisense
TAAGTTTTGCTCTATCTTTCTTTCT 625 637 1080 Antisense
TCTCTTTCTCTTCCTTATATTTATA 336 613 1112 Antisense
TCTCTTCCTTATATTTATACATCTA 418 613 1118 Antisense
GTTAGATATTCACATCTTGTTTATC 204 447 1146 Antisense
TTCACATCTTGTTTATCATCAGAAA 360 685 1154 Antisense
GAAACAACACTATTTATACCCAATT 422 351 1175 Antisense
TACCCAATTAGATAATACCCAGGGA 194 1 1191 Antisense
TACCCAGGGATCGAGAAGATCCGGA 277 649 1206 Antisense
GATCCGGAAGATCCGCTTGCTTTCA 661 415 1223 Antisense
Sequence Source GenBank