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[173416_at] G2/M Cyclin A

Description g732462-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g732462 /5_PRIME_EXT_DB=GenBank Identifier /CHR=3 /FEA=Genomic Cluster /DEF=cyclin A
Cluster 6grp_highest_10_10 > 96      6grp_high1_10_10 > 68      4grp_highest_8_8 > 49      4grp_high_8_8 > 42      6grp_highest_nonorm > 92      6grp_total > 69      4grp_total > 54      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 125
1 2 3 4 range
A 238.9
(3)
P 		208.3
(1.2)
P 		183.5
(-0.3)
P 		138.7
(-3)
P 		100
B 227.2
(2.4)
P 		239.8
(3)
P 		178.2
(0.1)
P 		114.4
(-3)
P 		125
C 201.5
(2.1)
P 		121.4
(-3)
P 		163.6
(-0.3)
P 		215.7
(3)
P 		94
avr 222.5
(3) 		189.8
(0) 		175.1
(-1.3) 		156.3
(-3) 		66

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 304
1 2 3 4 5 6 range
A 287.6
(-0.3)
P 		215.8
(-1.9)
P 		166.1
(-3)
P 		213.6
(-1.9)
P 		338.7
(0.8)
P 		436.6
(3)
P 		271
B 233
(-2)
P 		274.6
(-1.1)
P 		183.8
(-3)
P 		185.4
(-3)
P 		252.8
(-1.6)
P 		470
(3)
P 		286
C 214.8
(-2)
P 		274.5
(-0.7)
P 		166.5
(-3)
P 		171.8
(-2.9)
P 		219
(-1.9)
P 		447
(3)
P 		281
avr 245.1
(-1.4) 		255
(-1.2) 		172.1
(-3) 		190.3
(-2.6) 		270.2
(-0.9) 		451.2
(3) 		279
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 87
(3)
P 		45.2
(-0.8)
P 		48
(-0.5)
P 		20.3
(-3)
P 		67
B 72.4
(3)
P 		59.2
(1.4)
P 		41.3
(-0.9)
P 		24.4
(-3)
P 		48
C 66.7
(3)
P 		34.9
(-3)
P 		57
(1.2)
P 		36.4
(-2.7)
P 		32
avr 75.4
(3) 		46.4
(-0.6) 		48.8
(-0.3) 		27
(-3) 		48

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 141
1 2 3 4 5 6 range
A 53
(-1.6)
P 		76.7
(0.5)
P 		36.2
(-3)
P 		54.2
(-1.5)
P 		102.2
(2.6)
P 		106.3
(3)
P 		70
B 81.1
(-1.3)
P 		91.4
(-0.9)
P 		44.6
(-3)
P 		49.1
(-2.8)
P 		102.7
(-0.3)
P 		175.3
(3)
P 		131
C 79.6
(-0.7)
P 		83.8
(-0.4)
P 		42.4
(-2.6)
P 		34.6
(-3)
P 		70.9
(-1.1)
P 		149.6
(3)
P 		115
avr 71.2
(-1.2) 		84
(-0.5) 		41.1
(-3) 		46
(-2.7) 		91.9
(-0) 		143.7
(3) 		103
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173416_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.24025
Sequence Type Exemplar sequence
Representative Public ID 732462 NCBI
Target Description g732462-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g732462 /5_PRIME_EXT_DB=GenBank Identifier /CHR=3 /FEA=Genomic Cluster /DEF=cyclin A
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066617(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066617 NCBI Caenorhabditis elegans ZK507.6 (ZK507.6) mRNA, complete cds. 11/11 A 
ZK507.6 ENSEMBL cdna:known chromosome:CEL140:III:9106607:9109178:-1 gene:ZK507.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:9106603-9109177(-) 100.0 100.0
Public Domain and Genome References
Gene Title G2/M Cyclin A
Ensembl ZK507.6
Entrez Gene 176287 Entrez gene
SwissProt P34638 EMBL-EBI
WormBase CE03820 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260505_AT cyclin, putative at
CANINE_2:CFAAFFX.7108.1.S1_AT similar to Cyclin A2 (Cyclin A) cfa
DROSOPHILA_2:1639195_A_AT Cyclin A dm
DROSGENOME1:155068_AT Cyclin A dm
CHICKEN:GGA.4129.1.S1_AT cyclin A2 gga
HG-U95AV2:1943_AT cyclin A2 hs
HC-G110:1943_AT cyclin A2 hs
HG-U133A_2:203418_AT cyclin A2 hs
HG-U133A:203418_AT cyclin A2 hs
HG-U133_PLUS_2:203418_AT cyclin A2 hs
HG-FOCUS:203418_AT cyclin A2 hs
HUGENEFL:X51688_AT cyclin A2 hs
U133_X3P:G4502612_3P_AT cyclin A2 hs
HG-U95AV2:40697_AT cyclin A2 hs
HG-U133_PLUS_2:213226_AT Cyclin A2 hs
HG-U133A_2:213226_AT Cyclin A2 hs
HG-FOCUS:213226_AT Cyclin A2 hs
HG-U133A:213226_AT Cyclin A2 hs
HU35KSUBA:AA424282_AT Cyclin A2 hs
U133_X3P:HS.91728.1.A1_3P_AT Cyclin A2 hs
MU11KSUBB:Z26580_S_AT cyclin A2 mm
MG-U74AV2:99186_AT cyclin A2 mm
MOE430A:1417911_AT cyclin A2 mm
MOUSE430A_2:1417911_AT cyclin A2 mm
MOUSE430_2:1417911_AT cyclin A2 mm
MOE430A:1417910_AT cyclin A2 mm
MOUSE430A_2:1417910_AT cyclin A2 mm
MOUSE430_2:1417910_AT cyclin A2 mm
MU19KSUBA:TC18751_S_AT Cyclin A2 (Ccna2), mRNA mm
MU19KSUBB:TC34515_I_AT Cyclin A2 (Ccna2), mRNA mm
MU19KSUBB:TC34515_S_AT Cyclin A2 (Ccna2), mRNA mm
MU19KSUBC:TC41283_I_AT Cyclin A2 (Ccna2), mRNA mm
MU19KSUBC:TC41283_S_AT Cyclin A2 (Ccna2), mRNA mm
RG-U34B:RC_AA998516_AT cyclin A2 rn
RAE230B:1379582_A_AT cyclin A2 rn
RAT230_2:1379582_A_AT cyclin A2 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
74 regulation of progression through cell cycle inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA82372 Hypothetical protein ZK507.6 [Caenorhabditis elegans] ref|NP_499018.1| ZK507.6 [Caenorhabditis elegans] sp|P34638|CCNA1_CAEEL G2/mitotic-specific cyclin A1 gb|AAA84393.1| cyclin A 0.0
blast CAE62767 Hypothetical protein CBG06936 [Caenorhabditis briggsae] 1.0E-128
blast AAC35953 cyclin A [Dreissena polymorpha] 8.0E-42
Protein Domains
Database ID Description E-Value
Pfam IPR004367 EMBL-EBI Cyclin, C-terminal 5.1E-34
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 6.2E-49
Sequence
Target Sequence 
>C. ELEGANS:173416_AT
ttgaattctccaaatttcccgactttcaatttcattccctgtctttgtttgcctttatcg
attacatcttctaaaattctccttttaaaactacgattttatgtaacaattctttgtatt
tgtataactcatcccgacaggaatcggaacatacacggatatgatccgatattaaaaatt
ccttttttgtgttatatgtaatagtattatcagtgctctccatccacccccttatctggc
tgttttacagctttttctccagttttcttatttatttatgatactcctggcttggcaact
atgatctatgattcctttttgttccgagccgtaatttacgcactgcgctcattgttttat
atttgttccacgatctcatctcgtagttgctctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGAATTCTCCAAATTTCCCGACTT 184 705 1562 Antisense
GACTTTCAATTTCATTCCCTGTCTT 13 373 1582 Antisense
CTGTCTTTGTTTGCCTTTATCGATT 393 239 1600 Antisense
GTATTTGTATAACTCATCCCGACAG 659 451 1677 Antisense
GCTGTTTTACAGCTTTTTCTCCAGT 414 293 1800 Antisense
TATGATACTCCTGGCTTGGCAACTA 603 655 1838 Antisense
GATCTATGATTCCTTTTTGTTCCGA 691 419 1864 Antisense
GAGCCGTAATTTACGCACTGCGCTC 28 387 1887 Antisense
CGCACTGCGCTCATTGTTTTATATT 248 255 1900 Antisense
GTTTTATATTTGTTCCACGATCTCA 361 449 1915 Antisense
ACGATCTCATCTCGTAGTTGCTCTC 62 93 1931 Antisense
Sequence Source GenBank