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[173405_s_at] fumarylacetoacetase

Description AV200177_rc /REP_DB=TREMBL Accession /GB=AV200177 /FEA=Transcript Cluster /DEF=Caenorhabditis elegans cDNA clone:yk557h8 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 15      6grp_high1_10_10 > 40      4grp_highest_8_8 > 12      4grp_high_8_8 > 39      6grp_highest_nonorm > 43      6grp_total > 41      4grp_total > 40      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 570
1 2 3 4 range
A 1334.7
(-3)
P 		1716.8
(3)
P 		1547.6
(0.3)
P 		1552
(0.4)
P 		382
B 1317.4
(-1.3)
P 		1237.3
(-3)
P 		1516.7
(3)
P 		1477.5
(2.2)
P 		279
C 1146.6
(-3)
P 		1471.3
(1.6)
P 		1568.3
(3)
P 		1341.1
(-0.2)
P 		422
avr 1266.2
(-3) 		1475.1
(1.5) 		1544.2
(3) 		1456.9
(1.1) 		278

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1516
1 2 3 4 5 6 range
A 1345.3
(0.1)
P 		1355.1
(0.1)
P 		2088.5
(3)
P 		1498.7
(0.7)
P 		896.5
(-1.7)
P 		572.1
(-3)
P 		1516
B 1252.2
(-0.6)
P 		1319.2
(-0.3)
P 		2044.5
(3)
P 		1525.9
(0.7)
P 		1015
(-1.7)
P 		716.7
(-3)
P 		1328
C 1252.6
(-0.1)
P 		1414.5
(0.7)
P 		1854.6
(3)
P 		1449.5
(0.9)
P 		927.4
(-1.8)
P 		704.5
(-3)
P 		1150
avr 1283.4
(-0.2) 		1362.9
(0.1) 		1995.9
(3) 		1491.4
(0.7) 		946.3
(-1.7) 		664.4
(-3) 		1332
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 321
1 2 3 4 range
A 486
(3)
P 		372.7
(0.4)
P 		404.6
(1.1)
P 		227.2
(-3)
P 		259
B 420.1
(3)
P 		305.6
(-3)
P 		351.5
(-0.6)
P 		314.9
(-2.5)
P 		115
C 379.6
(-0.1)
P 		423
(0.7)
P 		546.6
(3)
P 		226.1
(-3)
P 		321
avr 428.6
(2.8) 		367.1
(0.7) 		434.2
(3) 		256.1
(-3) 		178

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 357
1 2 3 4 5 6 range
A 248
(-1.1)
P 		482
(3)
P 		454.8
(2.5)
P 		380.1
(1.2)
P 		270.5
(-0.7)
P 		139.3
(-3)
P 		343
B 435.7
(1.4)
P 		439.1
(1.5)
P 		496.5
(3)
P 		404.2
(0.6)
P 		412.4
(0.8)
P 		267.3
(-3)
P 		229
C 464.3
(2.8)
P 		431.6
(2)
P 		472
(3)
P 		291.5
(-1.6)
P 		300.1
(-1.4)
P 		235.8
(-3)
P 		236
avr 382.7
(0.9) 		450.9
(2.5) 		474.4
(3) 		358.6
(0.3) 		327.7
(-0.4) 		214.1
(-3) 		260
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173405_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.27697
Sequence Type Exemplar sequence
Representative Public ID AV200177 NCBI
Target Description AV200177_rc /REP_DB=TREMBL Accession /GB=AV200177 /FEA=Transcript Cluster /DEF=Caenorhabditis elegans cDNA clone:yk557h8 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Transcript Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076682(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076682 NCBI Caenorhabditis elegans K10C2.4 (fumarylacetoacetase) mRNA, complete cds. 11/11 A 
SNAP00000032620 ENSEMBL cdna:SNAP chromosome:CEL140:X:6446787:6448863:-1 11/11 None
GENEFINDER00000032623 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6446787:6448863:-1 11/11 None
K10C2.4.1 ENSEMBL cdna:known chromosome:CEL140:X:6446604:6448954:-1 gene:K10C2.4 11/11 None
K10C2.4.2 ENSEMBL cdna:known chromosome:CEL140:X:6446604:6448871:-1 gene:K10C2.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6446771-6447060(-) 86.89 86.89
Public Domain and Genome References
Gene Title fumarylacetoacetase
Ensembl K10C2.4
Entrez Gene 180918 Entrez gene
SwissProt Q94272 EMBL-EBI
WormBase CE04750 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264396_AT fumarylacetoacetase, putative at
ATGENOME1:19258_AT fumarylacetoacetase, putative at
CANINE:1587265_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
CANINE_2:CFA.14908.1.A1_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
CANINE_2:CFA.14908.1.A1_S_AT similar to Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) cfa
DROSOPHILA_2:1638810_AT Fumarylacetoacetase dm
DROSGENOME1:142340_AT Fumarylacetoacetase dm
CHICKEN:GGA.9670.1.S1_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) gga
HG-U133A:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133A_2:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133_PLUS_2:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-FOCUS:202862_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HU35KSUBD:RC_W79422_S_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HUGENEFL:M55150_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
U133_X3P:G4557586_3P_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U95AV2:36876_AT fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133_PLUS_2:236481_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U133B:236481_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HU35KSUBB:RC_T97217_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
U133_X3P:HS.18001.0.S1_3P_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
HG-U95B:48002_AT Fumarylacetoacetate hydrolase (fumarylacetoacetase) hs
MU11KSUBA:M84145_S_AT fumarylacetoacetate hydrolase mm
MG-U74AV2:98588_AT fumarylacetoacetate hydrolase mm
MOE430A:1417220_AT fumarylacetoacetate hydrolase mm
MOUSE430A_2:1417220_AT fumarylacetoacetate hydrolase mm
MOUSE430_2:1417220_AT fumarylacetoacetate hydrolase mm
MU19KSUBC:TC36660_S_AT Fumarylacetoacetate hydrolase, mRNA (cDNA clone MGC:18569 IMAGE:4242421) mm
RAT230_2:1368092_AT fumarylacetoacetate hydrolase rn
RAE230A:1368092_AT fumarylacetoacetate hydrolase rn
RG-U34A:M77694_AT fumarylacetoacetate hydrolase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
9072 aromatic amino acid family metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
4334 fumarylacetoacetase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK39259 Hypothetical protein K10C2.4 [Caenorhabditis elegans] ref|NP_509083.1| K10C2.4 [Caenorhabditis elegans] 0.0
blast CAE61259 Hypothetical protein CBG05065 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002529 EMBL-EBI Fumarylacetoacetate (FAA) hydrolase 2.5E-115
Sequence
Target Sequence 
>C. ELEGANS:173405_S_AT
accacaccgtcaatggatgcaacctccgcgctggagatcttttgggatcaggaactgtat
ctggannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngtggcgcggagccaaag
aagttccagttggctcagaaatccgaaagttcttaaaggacggagatgaggtcaaccagt
tccccgaggttgtgtgtagtaatggagtccgtgagttggtttcggagagtgccgcggaaa
agtcc

BLASTn GenBank NR
Note: "n"'s represent regions that are not probed by the probe sequences.
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACCACACCGTCAATGGATGCAACCT 523 85 40 Antisense
ACACCGTCAATGGATGCAACCTCCG 259 109 43 Antisense
CAACCTCCGCGCTGGAGATCTTTTG 285 187 59 Antisense
CTCCGCGCTGGAGATCTTTTGGGAT 133 235 63 Antisense
TTTGGGATCAGGAACTGTATCTGGA 38 667 80 Antisense
GGCGCGGAGCCAAAGAAGTTCCAGT 205 541 145 Antisense
AGTTCCAGTTGGCTCAGAAATCCGA 75 65 161 Antisense
GGCTCAGAAATCCGAAAGTTCTTAA 239 537 171 Antisense
TTAAAGGACGGAGATGAGGTCAACC 631 523 192 Antisense
TTGGTTTCGGAGAGTGCCGCGGAAA 61 655 255 Antisense
TTCGGAGAGTGCCGCGGAAAAGTCC 344 693 260 Antisense
Sequence Source Affymetrix Proprietary Database