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[173387_at]

Description g9837167-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g9837167 /5_PRIME_EXT_DB=GenBank Identifier /CHR=3 /FEA=Genomic Cluster /DEF=MAB-5
Cluster 6grp_highest_10_10 > 43      6grp_high1_10_10 > 23      4grp_highest_8_8 > 63      4grp_high_8_8 > 28      6grp_highest_nonorm > 70      6grp_total > 12      4grp_total > 35      6grp_highest_sub > 02      6grp_cgc > 62      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 161
1 2 3 4 range
A 340.5
(3)
P 		333.3
(2.5)
P 		308.3
(0.8)
P 		251.8
(-3)
P 		89
B 228.2
(-3)
P 		339.4
(3)
P 		265.2
(-1)
P 		283.2
(-0)
P 		111
C 294.1
(-0.7)
P 		307.8
(-0.2)
P 		235.7
(-3)
P 		388.7
(3)
P 		153
avr 287.6
(-1.1) 		326.8
(3) 		269.7
(-3) 		307.9
(1) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 263
1 2 3 4 5 6 range
A 284.2
(1.8)
P 		311.9
(3)
P 		303.7
(2.6)
P 		229.5
(-0.6)
P 		275.9
(1.4)
P 		175.6
(-3)
P 		136
B 204.5
(-2.6)
P 		332
(2)
P 		358.4
(3)
P 		259.3
(-0.6)
P 		281.3
(0.2)
P 		194.8
(-3)
P 		164
C 375.4
(2.1)
P 		412.7
(3)
P 		213.4
(-1.5)
P 		285.9
(0.1)
P 		221.6
(-1.4)
P 		149.7
(-3)
P 		263
avr 288
(0.8) 		352.2
(3) 		291.8
(1) 		258.2
(-0.2) 		259.6
(-0.1) 		173.4
(-3) 		179
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 87
1 2 3 4 range
A 124
(3)
P 		72.3
(-0.6)
P 		80.6
(0)
P 		36.9
(-3)
P 		87
B 72.8
(0.2)
P 		83.8
(3)
P 		61.5
(-2.7)
P 		60.3
(-3)
P 		24
C 97.4
(3)
P 		88.5
(1.3)
P 		82.1
(0.1)
P 		65.5
(-3)
P 		32
avr 98.1
(3) 		81.5
(0.7) 		74.7
(-0.2) 		54.2
(-3) 		44

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 96
1 2 3 4 5 6 range
A 52.4
(-2.2)
P 		110.9
(3)
P 		66.1
(-0.9)
P 		58.2
(-1.6)
P 		83.3
(0.6)
P 		42.8
(-3)
P 		68
B 71.2
(-2.7)
P 		110.5
(2.5)
P 		87
(-0.6)
P 		68.7
(-3)
P 		114.3
(3)
P 		72.6
(-2.5)
P 		46
C 139.1
(3)
P 		125.9
(2.1)
P 		54.3
(-2.7)
P 		57.5
(-2.5)
P 		71.7
(-1.5)
P 		50.1
(-3)
P 		89
avr 87.6
(0.2) 		115.8
(3) 		69.1
(-1.6) 		61.5
(-2.4) 		89.8
(0.4) 		55.2
(-3) 		61
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 173387_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23932
Sequence Type Exemplar sequence
Representative Public ID 9837167 NCBI
Target Description g9837167-REP_DB=GenBank Identifier /5_PRIME_EXT_ID=g9837167 /5_PRIME_EXT_DB=GenBank Identifier /CHR=3 /FEA=Genomic Cluster /DEF=MAB-5
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066294(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066294 NCBI Caenorhabditis elegans Male ABnormal family member (mab-5) (mab-5) mRNA, complete cds. 11/11 A 
C08C3.3 ENSEMBL cdna:known chromosome:CEL140:III:7776830:7783378:-1 gene:C08C3.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7776828-7783376(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol mab-5
Ensembl C08C3.3
Entrez Gene 176091 Entrez gene
SwissProt P10038 EMBL-EBI
WormBase CE25765 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1585156_AT similar to Homeobox protein Hox-B7 (Hox-2C) (HHO.C1) cfa
CANINE_2:CFA.15630.1.A1_AT similar to Homeobox protein Hox-B7 (Hox-2C) (HHO.C1) cfa
CANINE_2:CFAAFFX.25773.1.S1_AT similar to Homeobox protein Hox-B7 (Hox-2C) (HHO.C1) cfa
HG-U133_PLUS_2:204779_S_AT homeo box B7 hs
HG-U133A_2:204779_S_AT homeo box B7 hs
HG-U133A:204779_S_AT homeo box B7 hs
HUGENEFL:M16937_AT homeo box B7 hs
U133_X3P:HS.819.1.S1_3P_A_AT homeo box B7 hs
U133_X3P:HS.819.0.S1_3P_X_AT homeo box B7 hs
U133_X3P:HS.819.0.S1_3P_A_AT homeo box B7 hs
U133_X3P:204778_3P_X_AT homeo box B7 hs
HG-U133A_2:204778_X_AT homeo box B7 hs
HG-U133_PLUS_2:204778_X_AT homeo box B7 hs
HG-U133A:204778_X_AT homeo box B7 hs
HG-U133A_2:216973_S_AT homeo box B7 hs
HG-FOCUS:216973_S_AT homeo box B7 hs
HG-U133_PLUS_2:216973_S_AT homeo box B7 hs
HG-U133A:216973_S_AT homeo box B7 hs
HG-U95AV2:37618_AT homeo box B7 hs
MOUSE430A_2:1427494_AT homeo box B7 mm
MOE430A:1427494_AT homeo box B7 mm
MOUSE430_2:1427494_AT homeo box B7 mm
MU11KSUBB:X06762_S_AT homeo box B7 mm
MG-U74AV2:92914_AT homeo box B7 mm
MG-U74AV2:92915_S_AT homeo box B7 mm
MOE430A:1452493_S_AT homeo box B7 mm
MOUSE430A_2:1452493_S_AT homeo box B7 mm
MOUSE430_2:1452493_S_AT homeo box B7 mm
RAE230A:1388287_AT homeobox protein rn
RAT230_2:1388287_AT homeobox protein rn
RG-U34A:M37566CDS_AT homeobox protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA28106 DNA-binding protein mab5 2.0E-84
blast AAA27945 Male abnormal protein 5 [Caenorhabditis elegans] ref|NP_498695.1| Male ABnormal family member (mab-5) [Caenorhabditis elegans] gb|AAG00458.1| MAB-5 [Caenorhabditis elegans] sp|P10038|MAB5_CAEEL Homeobox protein mab-5 (Male abnormal-5 protein) 2.0E-84
blast AAG00457 MAB-5 [Caenorhabditis briggsae] emb|CAE57185.1| Hypothetical protein CBG00029 [Caenorhabditis briggsae] 5.0E-80
Protein Domains
Database ID Description E-Value
scop a.4.1.Homeodomain All alpha proteins; DNA/RNA-binding 3-helical bundle; Homeodomain-like; Homeodomain 4.99999984132761E-21
Pfam IPR001356 EMBL-EBI Homeobox 4.8E-30
Sequence
Target Sequence 
>C. ELEGANS:173387_AT
acattcttcttgattttcactttttttggtcagaatctaatttgaatttctttttacctc
gtttccggtcgcttttcattgttttgctcccatttttgtcattttcctttgattttttgc
attcttcatcggtgatatattgcttttaaacgacctgaaaggattccacgccctttcgac
gggtctttgtttttattgattatttctcaatttcttcctttgcttctttgggatttgatg
atctcaacctttgtctcgaaaattgttttttacacactgctagcctattttttgattttt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACATTCTTCTTGATTTTCACTTTTT 353 105 670 Antisense
GATTTTCACTTTTTTTGGTCAGAAT 462 429 681 Antisense
TTCATTGTTTTGCTCCCATTTTTGT 255 689 744 Antisense
ATTTTTTGCATTCTTCATCGGTGAT 477 15 781 Antisense
GATATATTGCTTTTAAACGACCTGA 371 423 803 Antisense
TGAAAGGATTCCACGCCCTTTCGAC 209 571 825 Antisense
TCGACGGGTCTTTGTTTTTATTGAT 189 601 845 Antisense
ATTTCTTCCTTTGCTTCTTTGGGAT 648 13 879 Antisense
TGATGATCTCAACCTTTGTCTCGAA 360 567 905 Antisense
GTTTTTTACACACTGCTAGCCTATT 289 449 934 Antisense
ACTGCTAGCCTATTTTTTGATTTTT 203 99 945 Antisense
Sequence Source GenBank