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[173362_s_at] CHL1 protein

Description AV200489_rc /REP_DB=TREMBL Accession /GB=AV200489 /FEA=Transcript Cluster /DEF=Caenorhabditis elegans cDNA clone:yk576a7 : 3prime end, single read.
Cluster 6grp_total > 87      4grp_total > 48      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 42.7
(-3)
A 		66
(0.6)
A 		81.3
(3)
A 		70.1
(1.3)
A 		39
B 74.5
(-0.9)
A 		101.7
(3)
A 		59.4
(-3)
A 		62.6
(-2.5)
A 		42
C 55.6
(-1)
A 		41.4
(-3)
A 		84.3
(3)
A 		55.2
(-1.1)
A 		43
avr 57.6
(-3) 		69.7
(1.2) 		75
(3) 		62.6
(-1.3) 		17

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 195
1 2 3 4 5 6 range
A 85.3
(-1)
A 		44.6
(-3)
A 		89.8
(-0.8)
A 		83.3
(-1.1)
M 		95.5
(-0.5)
P 		167.1
(3)
P 		123
B 59.6
(-2.4)
A 		80.7
(-1.8)
A 		41.1
(-3)
A 		81.8
(-1.7)
P 		120.8
(-0.5)
P 		235.9
(3)
P 		195
C 76.5
(-2.8)
A 		71.7
(-3)
A 		72.7
(-3)
A 		118
(-1)
A 		152.3
(0.5)
P 		210.7
(3)
P 		139
avr 73.8
(-2.7) 		65.7
(-3) 		67.9
(-2.9) 		94.4
(-1.8) 		122.9
(-0.5) 		204.6
(3) 		139
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 20
1 2 3 4 range
A 15.5
(-0.2)
A 		14.3
(-0.8)
A 		21.3
(3)
A 		10.3
(-3)
A 		11
B 23.8
(2.3)
A 		25.1
(3)
A 		13.8
(-2.7)
A 		13.3
(-3)
A 		12
C 18.4
(-0.3)
A 		11.9
(-2.2)
A 		29.4
(3)
A 		9.3
(-3)
A 		20
avr 19.2
(1.7) 		17.1
(0.5) 		21.5
(3) 		11
(-3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 78
1 2 3 4 5 6 range
A 15.7
(-3)
A 		15.9
(-3)
A 		19.6
(-2.1)
A 		21.1
(-1.7)
M 		28.8
(0.1)
P 		40.7
(3)
P 		25
B 20.7
(-2.2)
A 		26.9
(-1.7)
A 		10
(-3)
A 		21.7
(-2.1)
P 		49.1
(0)
P 		88
(3)
P 		78
C 28.3
(-1.9)
A 		21.9
(-2.6)
A 		18.5
(-3)
A 		23.7
(-2.4)
A 		49.3
(0.6)
P 		70.5
(3)
P 		52
avr 21.6
(-2.3) 		21.6
(-2.3) 		16
(-3) 		22.2
(-2.3) 		42.4
(0.1) 		66.4
(3) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173362_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.27939
Sequence Type Exemplar sequence
Representative Public ID AV200489 NCBI
Target Description AV200489_rc /REP_DB=TREMBL Accession /GB=AV200489 /FEA=Transcript Cluster /DEF=Caenorhabditis elegans cDNA clone:yk576a7 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Transcript Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066894(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066894 NCBI Caenorhabditis elegans M03C11.2 (M03C11.2) mRNA, complete cds. 11/11 A 
SNAP00000000515 ENSEMBL cdna:SNAP chromosome:CEL140:III:10399179:10405121:-1 11/11 None
GENEFINDER00000000554 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10399179:10405121:-1 11/11 None
M03C11.2 ENSEMBL cdna:known chromosome:CEL140:III:10398705:10405122:-1 gene:M03C11.2 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10399165-10399944(-) 90.88 90.88
Public Domain and Genome References
Gene Title CHL1 protein
Ensembl M03C11.2
Entrez Gene 176457 Entrez gene
SwissProt Q21489 EMBL-EBI
WormBase CE03493 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260159_AT helicase-related at
CANINE_2:CFAAFFX.24097.1.S1_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
CANINE_2:CFAAFFX.24097.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
CANINE_2:CFAAFFX.24099.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 cfa
DROSOPHILA_2:1626359_AT dm
DROSGENOME1:154240_AT dm
CHICKEN:GGA.11265.1.A1_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
CHICKEN:GGAAFFX.24068.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
CHICKEN:GGAAFFX.8207.1.S1_S_AT similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; yeast CHL1 homolog; DEAD/H box-11 (CHL1-related helicase gene-1); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase) gga
HG-U133_PLUS_2:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:208159_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-FOCUS:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:208149_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:232816_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133B:232816_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:210206_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBA:U75968_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBA:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBB:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBC:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HU35KSUBD:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HUGENEFL:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HC-G110:HUM_ALU_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HUGENEFL:U75968_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G1517815_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G13787196_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:HS.129998.3.S1_3P_X_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A_2:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-FOCUS:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133_PLUS_2:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U133A:213378_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95AV2:31935_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95C:57224_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:89108_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
U133_X3P:G13787196_3P_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95C:57224_S_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:73694_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:73062_R_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) hs
HG-U95D:86738_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae) hs
MG-U74BV2:111583_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOE430B:1438447_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOUSE430_2:1438447_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOE430B:1441062_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
MOUSE430_2:1441062_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) mm
RAE230B:1395376_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAT230_2:1395376_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAE230B:1391118_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
RAT230_2:1391118_AT DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (predicted) rn
YEAST_2:1777889_AT Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism inferred from electronic annotation QuickGO AmiGO
6289 nucleotide-excision repair inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
4003 ATP-dependent DNA helicase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8026 ATP-dependent helicase activity inferred from electronic annotation QuickGO AmiGO
16818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88959 Hypothetical protein M03C11.2 [Caenorhabditis elegans] ref|NP_499295.1| M03C11.2 [Caenorhabditis elegans] 0.0
blast CAE71476 Hypothetical protein CBG18394 [Caenorhabditis briggsae] 0.0
blast NP_001007320 hypothetical protein LOC492353 [Danio rerio] gb|AAH85645.1| Zgc:92172 [Danio rerio] 1.0E-127
blast NP_001007320 hypothetical protein LOC492353 [Danio rerio] gb|AAH85645.1| Zgc:92172 [Danio rerio] 1.0E-125
Protein Domains
Database ID Description E-Value
Pfam IPR010614 EMBL-EBI DEAD_2 1.1E-76
Pfam IPR010614 EMBL-EBI DEAD_2 4.6E-82
Pfam IPR010614 EMBL-EBI DEAD_2 4.6E-82
Sequence
Target Sequence 
>C. ELEGANS:173362_S_AT
aagaccagcgtcgagttgagggaacggatgaagttcctcgacactcaaatgccgaacggt
ggaaacctgctntacgaatcnnnnnnnnnnnnnnnnnnnnnnnnnnnncatcggtcgagc
aatccgtcaccgccgagactacgcggccgtctatctcttcgacgaccgctacgcaaagga
gtccactcggagaaagttgtccacgtggattggagatcgcactcaagtcaagttgggatt
tggcgagattattcgaaag

BLASTn GenBank NR
Note: "n"'s represent regions that are not probed by the probe sequences.
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGACCAGCGTCGAGTTGAGGGAAC 664 149 16 Antisense
GAGGGAACGGATGAAGTTCCTCGAC 154 383 33 Antisense
TGAAGTTCCTCGACACTCAAATGCC 489 575 44 Antisense
GTTCCTCGACACTCAAATGCCGAAC 262 441 48 Antisense
AAATGCCGAACGGTGGAAACCTGCT 323 117 62 Antisense
TTCGACGACCGCTACGCAAAGGAGT 156 697 173 Antisense
CGCTACGCAAAGGAGTCCACTCGGA 300 255 182 Antisense
CACTCGGAGAAAGTTGTCCACGTGG 520 197 199 Antisense
GTCCACGTGGATTGGAGATCGCACT 702 475 214 Antisense
GGAGATCGCACTCAAGTCAAGTTGG 88 517 227 Antisense
GGGATTTGGCGAGATTATTCGAAAG 647 495 250 Antisense
Sequence Source Affymetrix Proprietary Database