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[173188_s_at] transducin-like enhancer protein

Description AV181543_rc /REP_DB=TREMBL Accession /FEA=EST Transcript /REVCOMP /GB=AV181543 /DEF=Caenorhabditis elegans cDNA clone:yk621g4 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 65      6grp_high1_10_10 > 56      4grp_highest_8_8 > 49      4grp_high_8_8 > 41      6grp_highest_nonorm > 77      6grp_total > 57      4grp_total > 54      6grp_cgc > 37      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 522
1 2 3 4 range
A 1462.1
(3)
P 		1013.9
(-2.2)
P 		991.7
(-2.4)
P 		940.5
(-3)
P 		522
B 1136.6
(0.4)
P 		1163.9
(3)
P 		1120.8
(-1.1)
P 		1101.1
(-3)
P 		63
C 1338.8
(3)
P 		1230.1
(1.3)
P 		1149.5
(0)
P 		960.1
(-3)
P 		379
avr 1312.5
(3) 		1136
(-0.4) 		1087.3
(-1.3) 		1000.6
(-3) 		312

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 969
1 2 3 4 5 6 range
A 1046.1
(-2.7)
P 		1572.5
(0.6)
P 		993
(-3)
P 		1148.1
(-2)
P 		1083.4
(-2.4)
P 		1959.5
(3)
P 		967
B 1277.8
(-0.6)
P 		1410.1
(0.5)
P 		998.1
(-2.9)
P 		1294.4
(-0.5)
P 		990.9
(-3)
P 		1705.2
(3)
P 		714
C 1432.4
(-0.5)
P 		1391.8
(-0.9)
P 		1406.9
(-0.7)
P 		1335.4
(-1.4)
P 		1152.1
(-3)
P 		1824.5
(3)
P 		672
avr 1252.1
(-1.6) 		1458.1
(0) 		1132.7
(-2.5) 		1259.3
(-1.5) 		1075.5
(-3) 		1829.7
(3) 		754
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 395
1 2 3 4 range
A 532.4
(3)
P 		220.1
(-1.7)
P 		259.2
(-1.2)
P 		137.7
(-3)
P 		395
B 362.5
(3)
P 		287.5
(-0.5)
P 		259.7
(-1.8)
P 		234.6
(-3)
P 		128
C 443.2
(3)
P 		353.7
(1.1)
P 		400.6
(2.1)
P 		161.9
(-3)
P 		281
avr 446
(3) 		287.1
(-0.6) 		306.5
(-0.1) 		178.1
(-3) 		268

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 443
1 2 3 4 5 6 range
A 192.8
(-3)
P 		559.2
(3)
P 		216.3
(-2.6)
P 		291.2
(-1.4)
P 		326.9
(-0.8)
P 		477.1
(1.7)
P 		366
B 444.6
(0.1)
P 		469.4
(0.5)
P 		242.4
(-3)
P 		342.8
(-1.5)
P 		402.6
(-0.6)
P 		635.9
(3)
P 		394
C 530.9
(1.6)
P 		424.7
(-0.3)
P 		358.1
(-1.4)
P 		268.5
(-3)
P 		372.8
(-1.2)
P 		610.8
(3)
P 		342
avr 389.4
(-0.7) 		484.4
(1.2) 		272.3
(-3) 		300.8
(-2.4) 		367.4
(-1.1) 		574.6
(3) 		302
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 173188_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.26749
Sequence Type Exemplar sequence
Representative Public ID AV181543 NCBI
Target Description AV181543_rc /REP_DB=TREMBL Accession /FEA=EST Transcript /REVCOMP /GB=AV181543 /DEF=Caenorhabditis elegans cDNA clone:yk621g4 : 3prime end, single read.
Cluster Evidence This cluster is supported by a EST Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059531(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059531 NCBI Caenorhabditis elegans UNCoordinated family member (unc-37) (unc-37) mRNA, complete cds. 11/11 A 
SNAP00000042723 ENSEMBL cdna:SNAP chromosome:CEL140:I:6750658:6753458:-1 11/11 None
GENEFINDER00000042737 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6750658:6753458:-1 11/11 None
W02D3.9.2 ENSEMBL cdna:known chromosome:CEL140:I:6750124:6753463:-1 gene:W02D3.9 11/11 None
W02D3.9.1 ENSEMBL cdna:known chromosome:CEL140:I:6750124:6753473:-1 gene:W02D3.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6750563-6750722(-) 88.33 88.33
Public Domain and Genome References
Gene Title transducin-like enhancer protein
Gene Symbol unc-37
Ensembl W02D3.9
Entrez Gene 172394 Entrez gene
SwissProt O02482 EMBL-EBI
WormBase CE14434 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1605658_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) cfa
CANINE_2:CFA.2411.1.A1_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) cfa
CANINE_2:CFAAFFX.3217.1.S1_S_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) cfa
CANINE_2:CFAAFFX.3254.1.S1_S_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) cfa
CHICKEN:GGA.126.1.S1_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) gga
HG-U95AV2:38364_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133_PLUS_2:204872_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A:204872_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A_2:204872_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HU35KSUBC:RC_N26398_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HU35KSUBD:RC_AA491003_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HUGENEFL:M99439_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
U133_X3P:G5921462_3P_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
U133_X3P:HS.83958.1.S1_3P_A_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
U133_X3P:HS.83958.0.A1_3P_X_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
U133_X3P:HS.83958.0.A1_3P_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
U133_X3P:HS.296039.0.A1_3P_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A_2:214688_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133_PLUS_2:214688_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A:214688_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A_2:216997_X_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133_PLUS_2:216997_X_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133A:216997_X_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133_PLUS_2:233575_S_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133B:233575_S_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133_PLUS_2:235765_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U133B:235765_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U95AV2:40692_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U95B:51042_I_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U95B:51044_R_AT transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U95B:50137_AT Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HG-U95D:69701_AT Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
HU35KSUBA:RC_AA236922_AT Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) hs
MOUSE430_2:1425650_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOE430A:1425650_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOUSE430A_2:1425650_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOUSE430_2:1430384_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOE430B:1430384_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MU11KSUBA:U61363_S_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MU11KSUBA:C77702_RC_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MG-U74AV2:102959_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MG-U74CV2:166070_R_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOE430A:1450853_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOUSE430A_2:1450853_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MOUSE430_2:1450853_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
MU19KSUBC:TC40639_AT transducin-like enhancer of split 4, homolog of Drosophila E(spl) mm
RG-U34A:L14463_AT transducin-like enhancer of split 4, E(spl) homolog (Drosophila) rn
RAE230A:1387495_AT transducin-like enhancer of split 4, E(spl) homolog (Drosophila) rn
RAT230_2:1387495_AT transducin-like enhancer of split 4, E(spl) homolog (Drosophila) rn
RAE230A:1376869_AT Transducin-like enhancer of split 4, E(spl) homolog (Drosophila) rn
RAT230_2:1376869_AT Transducin-like enhancer of split 4, E(spl) homolog (Drosophila) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7222 frizzled signaling pathway inferred from electronic annotation QuickGO AmiGO
45449 regulation of transcription inferred from electronic annotation QuickGO AmiGO
16481 negative regulation of transcription inferred from sequence similarity QuickGO AmiGO
1505 regulation of neurotransmitter levels inferred from direct assay QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
5634 nucleus inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3714 transcription corepressor activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK21487 Uncoordinated protein 37 [Caenorhabditis elegans] ref|NP_491932.1| UNCoordinated family member (unc-37) [Caenorhabditis elegans] sp|O02482|UNC37_CAEEL Transcription factor unc-37 (Uncoordinated protein 37) gb|AAB84235.1| enhancer of split groucho [Caenorhabditis elegans] gb|AAB84234.1| enhancer of split groucho [Caenorhabditis elegans] 0.0
blast AAB49459 transcription factor UNC-37 [Caenorhabditis elegans] 0.0
blast CAE60442 Hypothetical protein CBG04050 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005617 EMBL-EBI Groucho/TLE N-terminal Q-rich domain 1.6E-12
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0024
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.14
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0012
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.0E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-6
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.49
Sequence
Target Sequence 
>C. ELEGANS:173188_S_AT
ctccatacggagcatcactctttcaactaaaagagaacagctccgttctctcatgtgaca
tctcattcgacgactcactcattgtcactggatcaggggagaagaaggcaactct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCCATACGGAGCATCACTCTTTCA 558 233 15 Antisense
ATACGGAGCATCACTCTTTCAACTA 61 25 19 Antisense
GGAGCATCACTCTTTCAACTAAAAG 700 519 23 Antisense
AAGAGAACAGCTCCGTTCTCTCATG 347 153 45 Antisense
CGTTCTCTCATGTGACATCTCATTC 57 249 58 Antisense
CATGTGACATCTCATTCGACGACTC 667 209 66 Antisense
TGACATCTCATTCGACGACTCACTC 190 571 70 Antisense
ATTCGACGACTCACTCATTGTCACT 509 9 79 Antisense
ACGACTCACTCATTGTCACTGGATC 412 91 84 Antisense
TCACTCATTGTCACTGGATCAGGGG 90 627 89 Antisense
GATCAGGGGAGAAGAAGGCAACTCT 423 421 105 Antisense
Sequence Source Affymetrix Proprietary Database