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[172920_x_at]

Description F11A6.1B /REP_DB=WormBase Gene ID /WP=CE17654 /GEN=kpc-1 /TR=O17798 /GB=CAB04085.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Subtilase family of serine proteases
Cluster 6grp_highest_10_10 > 93      6grp_high1_10_10 > 48      4grp_highest_8_8 > 23      4grp_high_8_8 > 13      6grp_highest_nonorm > 85      6grp_total > 48      4grp_total > 03      6grp_highest_sub > Cu      6grp_cgc > 18      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2262
1 2 3 4 range
A 1172.8
(-2.3)
P 		1195.9
(-2.2)
P 		900.3
(-3)
P 		3162
(3)
P 		2262
B 1217.4
(-2.4)
P 		1054.6
(-2.9)
P 		1029.5
(-3)
P 		2944.5
(3)
P 		1915
C 1249.9
(-1.9)
P 		1000.3
(-2.8)
P 		937.9
(-3)
P 		2661
(3)
P 		1723
avr 1213.4
(-2.2) 		1083.6
(-2.6) 		955.9
(-3) 		2922.5
(3) 		1967

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 416
1 2 3 4 5 6 range
A 980.7
(2.5)
P 		874.6
(0.8)
P 		642.2
(-3)
P 		666.2
(-2.6)
P 		755.2
(-1.2)
P 		1011
(3)
P 		369
B 918.1
(2.4)
P 		802
(0.4)
P 		595.2
(-3)
P 		785.6
(0.2)
P 		717.6
(-1)
P 		957
(3)
P 		362
C 886
(2.5)
P 		723.8
(-1.7)
P 		674.8
(-3)
P 		684.5
(-2.7)
P 		727.5
(-1.6)
P 		904
(3)
P 		229
avr 928.3
(2.5) 		800.1
(0.1) 		637.4
(-3) 		712.1
(-1.6) 		733.4
(-1.2) 		957.3
(3) 		320
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 392
1 2 3 4 range
A 427
(2.1)
P 		259.6
(-2.4)
P 		235.4
(-3)
P 		462.9
(3)
P 		228
B 388.2
(-0.7)
P 		260.5
(-2.7)
P 		238.6
(-3)
P 		627.5
(3)
P 		389
C 413.7
(1.7)
P 		287.6
(-3)
P 		326.9
(-1.5)
P 		448.7
(3)
P 		161
avr 409.6
(0.5) 		269.2
(-2.9) 		267
(-3) 		513
(3) 		246

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 219
1 2 3 4 5 6 range
A 180.8
(-1.6)
P 		311
(3)
P 		139.9
(-3)
P 		169
(-2)
P 		227.9
(0.1)
P 		246.2
(0.7)
P 		171
B 319.4
(1.9)
P 		267
(0.5)
P 		144.5
(-3)
P 		208.1
(-1.2)
P 		291.5
(1.2)
P 		356.9
(3)
P 		212
C 328.4
(3)
P 		220.9
(-0.4)
P 		171.7
(-1.9)
P 		137.7
(-3)
P 		235.4
(0.1)
P 		302.6
(2.2)
P 		191
avr 276.2
(2) 		266.3
(1.6) 		152
(-3) 		171.6
(-2.2) 		251.6
(1) 		301.9
(3) 		150
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172920_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1154
Sequence Type Exemplar sequence
Representative Public ID F11A6.1B NCBI
Target Description F11A6.1B /REP_DB=WormBase Gene ID /WP=CE17654 /GEN=kpc-1 /TR=O17798 /GB=CAB04085.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Subtilase family of serine proteases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060573(10), NM_001025929(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060573 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 10/11 A 
NM_001025929 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 11/11 None
SNAP00000041218 ENSEMBL cdna:SNAP chromosome:CEL140:I:11684167:11688754:1 10/11 None
GENEFINDER00000041221 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11688016:11688754:1 10/11 None
F11A6.1a ENSEMBL cdna:known chromosome:CEL140:I:11684065:11688874:1 gene:F11A6.1 10/11 A 
F11A6.1b ENSEMBL cdna:known chromosome:CEL140:I:11684066:11689089:1 gene:F11A6.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11684097-11688685(+) 90.93 100.0
Public Domain and Genome References
Ensembl F11A6.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB04086 Hypothetical protein F11A6.1a [Caenorhabditis elegans] ref|NP_492974.2| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
blast AAB63525 celfur protein 0.0
blast CAB04085 Hypothetical protein F11A6.1b [Caenorhabditis elegans] ref|NP_001021101.1| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 6.3E-74
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.0E-126
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000041221 1 159-176
Sequence
Target Sequence 
>C. ELEGANS:172920_X_AT
gaaatttccagggacttctacgcgttttcagaagtttccgaaaattctagaaattgagaa
aatgtttagaaattccaaaaaactccaagtttttagaaatatccccaacggaaaccgcct
tcaactccaactttactccgacggatgttatggtggagccgatgagaataaggtgtctta
tgtggagcacgtgcaggcaatcgtcacattgaaagctccaaaacgtggagatttgcaaat
ctacttgacttctccgtcaggcacaaaatccacgttgctcacaaaaagagcacgcgacac
atcacgaagtggcttcacagattgggctttcatgacgacccataactggggggagcaggc
cgccgggctgtggattctggaaatcgataatgatggatgggatgacgccgagcttgtaaa
atgggaactcgtgctctacggaactgatcgggaaaccggcgactttggaggccaacatgc
ttcaccgttagccgtcagaagtgtccagatggaagccacgtcatccggcacccaatattc
aattttccacgtcatcact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAATTTCCAGGGACTTCTACGCGT 513 361 1701 Antisense
TGGAGCACGTGCAGGCAATCGTCAC 246 549 1883 Antisense
TGCAAATCTACTTGACTTCTCCGTC 304 577 1934 Antisense
GACTTCTCCGTCAGGCACAAAATCC 638 369 1947 Antisense
GCACGCGACACATCACGAAGTGGCT 46 315 1990 Antisense
GTGGCTTCACAGATTGGGCTTTCAT 444 491 2009 Antisense
TGGATGGGATGACGCCGAGCTTGTA 25 551 2094 Antisense
GAACTCGTGCTCTACGGAACTGATC 338 347 2125 Antisense
CCGTTAGCCGTCAGAAGTGTCCAGA 272 261 2185 Antisense
CCAGATGGAAGCCACGTCATCCGGC 204 271 2205 Antisense
ATATTCAATTTTCCACGTCATCACT 198 19 2235 Antisense
Sequence Source Affymetrix Proprietary Database