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[172884_x_at] serine/threonine protein phosphatase

Description R08C7.8 /REP_DB=WormBase Gene ID /WP=CE07431 /TR=Q21840 /GB=AAC48076.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine protein phosphatase
Cluster 6grp_total > 78      4grp_total > 35      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 22.8
(-3)
A 		96.9
(3)
A 		35
(-2)
A 		23.9
(-2.9)
A 		74
B 19.7
(-3)
A 		63.2
(0.1)
A 		70.9
(0.6)
A 		104
(3)
A 		84
C 125.9
(3)
A 		75.8
(0.3)
A 		16.4
(-3)
A 		73.4
(0.1)
A 		110
avr 56.1
(-0.6) 		78.6
(3) 		40.8
(-3) 		67.1
(1.2) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 208
1 2 3 4 5 6 range
A 87.6
(-1)
A 		53.6
(-3)
A 		79.3
(-1.5)
A 		58.8
(-2.7)
A 		96.8
(-0.5)
A 		156.4
(3)
A 		103
B 24.5
(-2.4)
A 		17.4
(-2.7)
A 		9.6
(-3)
A 		50.8
(-1.4)
A 		132.3
(1.9)
A 		161.3
(3)
A 		152
C 73.5
(-1.2)
A 		53.6
(-1.8)
A 		12.8
(-3)
A 		15.6
(-2.9)
A 		38.2
(-2.3)
A 		217.2
(3)
A 		204
avr 61.9
(-1.8) 		41.5
(-2.7) 		33.9
(-3) 		41.7
(-2.7) 		89.1
(-0.7) 		178.3
(3) 		144
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 8.3
(-1.4)
A 		21
(3)
A 		9.1
(-1.1)
A 		3.5
(-3)
A 		18
B 6.3
(-3)
A 		15.6
(0.5)
A 		16.4
(0.8)
A 		22.2
(3)
A 		16
C 41.7
(3)
A 		21.8
(-0.3)
A 		5.7
(-3)
A 		12.4
(-1.9)
A 		36
avr 18.8
(2.5) 		19.5
(3) 		10.4
(-3) 		12.7
(-1.5) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 70
1 2 3 4 5 6 range
A 16.2
(-2.7)
A 		19.1
(-1.9)
A 		17.3
(-2.4)
A 		14.9
(-3)
A 		29.2
(0.7)
A 		38.1
(3)
A 		23
B 8.5
(-2.4)
A 		5.8
(-2.6)
A 		2.3
(-3)
A 		13.5
(-1.8)
A 		53.8
(2.3)
A 		60.2
(3)
A 		58
C 27.2
(-0.9)
A 		16.4
(-1.9)
A 		3.2
(-3)
A 		3.1
(-3)
A 		12.3
(-2.2)
A 		72.7
(3)
A 		70
avr 17.3
(-1.8) 		13.8
(-2.2) 		7.6
(-3) 		10.5
(-2.6) 		31.8
(-0.1) 		57
(3) 		49
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172884_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11101
Sequence Type Exemplar sequence
Representative Public ID R08C7.8 NCBI
Target Description R08C7.8 /REP_DB=WormBase Gene ID /WP=CE07431 /TR=Q21840 /GB=AAC48076.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=serine-threonine protein phosphatase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068162(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068162 NCBI Caenorhabditis elegans R08C7.8 (R08C7.8) mRNA, complete cds. 11/11 A 
SNAP00000031356 ENSEMBL cdna:SNAP chromosome:CEL140:IV:4433079:4434493:-1 11/11 None
GENEFINDER00000031369 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:4432677:4434493:-1 11/11 None
R08C7.8 ENSEMBL cdna:known chromosome:CEL140:IV:4433079:4434534:-1 gene:R08C7.8 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_074231 2/11 Cross Hyb Matching Probes A B 
SNAP00000001286 2/11 Cross Hyb Matching Probes None
GENEFINDER00000001294 2/11 Cross Hyb Matching Probes None
R08A2.2 2/11 Cross Hyb Matching Probes A B 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:4433084-4434475(-) 100.0 100.0
chrV:14716834-14718240(-) 95.31 95.31
Public Domain and Genome References
Gene Title serine/threonine protein phosphatase
Ensembl R08C7.8
Entrez Gene 177208 Entrez gene
SwissProt Q21840 EMBL-EBI
WormBase CE07431 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
16787 hydrolase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC48076 Hypothetical protein R08C7.8 [Caenorhabditis elegans] ref|NP_500563.1| R08C7.8 [Caenorhabditis elegans] 1.0E-180
blast CAB57902 Hypothetical protein R08A2.2 [Caenorhabditis elegans] ref|NP_506632.2| R08A2.2 [Caenorhabditis elegans] 1.0E-171
blast CAB57902 Hypothetical protein R08A2.2 [Caenorhabditis elegans] ref|NP_506632.2| R08A2.2 [Caenorhabditis elegans] 1.0E-168
blast CAE60846 Hypothetical protein CBG04555 [Caenorhabditis briggsae] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 1.3E-13
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 8.7E-8
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 1.3E-13
Pfam IPR004843 EMBL-EBI Metallo-phosphoesterase 8.7E-8
Sequence
Target Sequence 
>C. ELEGANS:172884_X_AT
gttggtcaacggatcctttgcatgcacggaggaatctcccaaaactgtaactcgtgggaa
tcattcaaagctctgaagaaaccgaatactccattaacctgtgacgaaggtcttcaagtt
gatttgatgtgggctgatccaactcaggataagtgcaacacgtttgcaatgaacaaacag
cgtgcaatttctgtagttttcggccaaaaaggattggatgatttcttgaagaagcttggc
ctctcgttgattgtccgagctcacgaagtgtctcaggaaggattcaacttcttgttcaac
aaaaagtgtgtcacagtgttctctgcgccatattattgtgggaatgataccaattgtgga
gcaattatgcacgtctcggattcttacgagctatccttcacagttctccgtccacgaatg
attgcaacaccagagaattttgaaattgtaaagctcatggagaacaactacaaagggctg
atggtcgcgagtccagatccaaaccgtggtcgtcatttgcaatctgctgatgttccccag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTGGTCAACGGATCCTTTGCATGC 338 433 388 Antisense
GTGCAATTTCTGTAGTTTTCGGCCA 582 481 569 Antisense
TTGGCCTCTCGTTGATTGTCCGAGC 426 709 623 Antisense
GTCCGAGCTCACGAAGTGTCTCAGG 28 477 640 Antisense
ACAGTGTTCTCTGCGCCATATTATT 555 107 700 Antisense
AATTATGCACGTCTCGGATTCTTAC 61 175 750 Antisense
TTACGAGCTATCCTTCACAGTTCTC 22 683 771 Antisense
ACAGTTCTCCGTCCACGAATGATTG 691 107 787 Antisense
GATGGTCGCGAGTCCAGATCCAAAC 41 407 867 Antisense
GATCCAAACCGTGGTCGTCATTTGC 457 415 883 Antisense
TTTGCAATCTGCTGATGTTCCCCAG 686 665 903 Antisense
Sequence Source Affymetrix Proprietary Database