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[172793_x_at] cathepsin protease

Description T10H4.12 /REP_DB=WormBase Gene ID /WP=CE27590 /GEN=cpr-3 /TR=Q9TW93 /GB=CAB61024.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=protease
Cluster 6grp_highest_10_10 > 01      6grp_high1_10_10 > 0      6grp_highest_nonorm > 62      6grp_total > 09      4grp_total > 54      6grp_cgc > 0      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 862
1 2 3 4 range
A 958
(3)
P 		534.1
(-0.2)
P 		542.2
(-0.2)
P 		166.9
(-3)
A 		791
B 1029
(3)
P 		611.5
(0.1)
P 		602.6
(-0)
P 		176.8
(-3)
A 		852
C 988.8
(3)
P 		504.7
(-0.6)
P 		475.2
(-0.8)
P 		171.4
(-3)
A 		817
avr 991.9
(3) 		550.1
(-0.2) 		540
(-0.3) 		171.7
(-3) 		820

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 420
1 2 3 4 5 6 range
A 718.5
(3)
P 		363.8
(-3)
P 		575.3
(0.6)
P 		504
(-0.6)
P 		451.7
(-1.5)
P 		440
(-1.7)
P 		355
B 597
(0.4)
P 		375
(-3)
P 		602.3
(0.5)
P 		761.5
(3)
P 		459.4
(-1.7)
P 		427.4
(-2.2)
P 		387
C 644.8
(3)
P 		341.3
(-3)
P 		547.7
(1.1)
P 		598.1
(2.1)
P 		399.6
(-1.8)
P 		452.4
(-0.8)
P 		304
avr 653.4
(3) 		360
(-3) 		575.1
(1.4) 		621.2
(2.3) 		436.9
(-1.4) 		439.9
(-1.4) 		293
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 324
1 2 3 4 range
A 348.8
(3)
P 		115.9
(-1.3)
P 		141.7
(-0.8)
P 		24.4
(-3)
A 		324
B 328.2
(3)
P 		151
(-0.7)
P 		139.6
(-0.9)
P 		37.7
(-3)
A 		291
C 327.3
(3)
P 		145.1
(-0.7)
P 		165.6
(-0.3)
P 		28.9
(-3)
A 		298
avr 334.8
(3) 		137.3
(-0.9) 		149
(-0.7) 		30.3
(-3) 		305

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 135
1 2 3 4 5 6 range
A 132.5
(2.2)
P 		129.4
(1.6)
P 		125.3
(0.7)
P 		127.8
(1.3)
P 		136.3
(3)
P 		107.1
(-3)
P 		29
B 207.7
(3)
P 		124.8
(-3)
P 		146.3
(-1.4)
P 		201.7
(2.6)
P 		186.6
(1.5)
P 		159.4
(-0.5)
P 		83
C 239
(3)
P 		104.1
(-3)
P 		139.4
(-1.4)
P 		120.3
(-2.3)
P 		129.3
(-1.9)
P 		151.5
(-0.9)
P 		135
avr 193.1
(3) 		119.4
(-3) 		137
(-1.6) 		149.9
(-0.5) 		150.7
(-0.5) 		139.3
(-1.4) 		74
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172793_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14543
Sequence Type Exemplar sequence
Representative Public ID T10H4.12 NCBI
Target Description T10H4.12 /REP_DB=WormBase Gene ID /WP=CE27590 /GEN=cpr-3 /TR=Q9TW93 /GB=CAB61024.2 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=protease
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074389(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074389 NCBI Caenorhabditis elegans Cysteine PRotease related family member (cpr-3) (cpr-3) mRNA, complete cds. 10/11 A 
T10H4.12 ENSEMBL cdna:known chromosome:CEL140:V:15299436:15301262:-1 gene:T10H4.12 10/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15299591-15301202(-) 100.0 100.0
Public Domain and Genome References
Gene Title cathepsin protease
Gene Symbol cpr-3
Ensembl T10H4.12
Entrez Gene 180033 Entrez gene
SwissProt P43507 EMBL-EBI
WormBase CE27590 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB61032 Hypothetical protein T10H4.12 [Caenorhabditis elegans] emb|CAB61024.2| Hypothetical protein T10H4.12 [Caenorhabditis elegans] ref|NP_506790.1| Cysteine PRotease related family member (cpr-3) [Caenorhabditis elegans] sp|P43507|CPR3_CAEEL Cathepsin B-like cysteine proteinase 3 precursor (Cysteine protease-related 3) gb|AAA98788.1| cathepsin B-like cysteine proteinase gb|AAA98782.1| cathepsin B-like cysteine proteinase 0.0
blast T24819 hypothetical protein T10H4.12 - Caenorhabditis elegans 1.0E-171
blast CAE71663 Hypothetical protein CBG18635 [Caenorhabditis briggsae] 1.0E-146
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 6.2E-107
Sequence
Target Sequence 
>C. ELEGANS:172793_X_AT
gacacggatgtatgccttactcgtttgctccgtgcacgaagaattgcccggagtcaacga
ctccaagctgtaagacaacttgccaatctagctacaaaacggaagaatacaaaaaggata
agcattatggtgagttggtctggcattcatttaatagatttcagaggtttctgaacagag
cttctgcctacaaagtcaccactacgaaatccgtcaccgaaattcaaactgaaatctacc
attacggacctgtggaggcttcatacaaagtctacgaggatttttatcattataaatcag
gagtttatcactatacttccggaaagcttgttggaggtcacgcggttaaaattatcggct
ggggagttgaaaacggagtggactactggctgattgcaaattcctggggcaccagtttcg
gcgaaaaggggttcttcaaaattcgccgtggaacaaatgaatgtcaaattgaaggaaacg
tggtagctggaattgcaaaattgggaacgcactcggaaacgtatgaagacgatggcggtg
cagcgacctcgtgtagttttatta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACACGGATGTATGCCTTACTCGTT 507 365 572 Antisense
TGCTCCGTGCACGAAGAATTGCCCG 617 581 597 Antisense
GACAACTTGCCAATCTAGCTACAAA 146 365 645 Antisense
ACAGAGCTTCTGCCTACAAAGTCAC 133 109 746 Antisense
AAGTCACCACTACGAAATCCGTCAC 705 155 764 Antisense
TGAAATCTACCATTACGGACCTGTG 434 571 801 Antisense
AAGCTTGTTGGAGGTCACGCGGTTA 333 151 895 Antisense
GGAGTGGACTACTGGCTGATTGCAA 87 515 946 Antisense
GATTGCAAATTCCTGGGGCACCAGT 529 427 963 Antisense
TGAAGACGATGGCGGTGCAGCGACC 57 575 1095 Antisense
GCAGCGACCTCGTGTAGTTTTATTA 182 309 1111 Antisense
Sequence Source Affymetrix Proprietary Database