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[172792_x_at] Cytochrome P450

Description H02I12.8 /REP_DB=WormBase Gene ID /WP=CE16163 /TR=O45605 /GB=CAB07222.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Cytochrome P450
Cluster 6grp_high1_10_10 > 98      4grp_high_8_8 > 19      6grp_total > 97      4grp_total > 21      6grp_cgc > 78      6grp_high1_sub > In      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 95
1 2 3 4 range
A 133.7
(0.9)
P 		134.5
(1)
P 		104.3
(-3)
A 		149.4
(3)
P 		45
B 147.2
(3)
P 		103.4
(-1.9)
A 		93.9
(-3)
P 		146.8
(3)
P 		53
C 146.4
(0.5)
P 		91
(-3)
A 		96.2
(-2.7)
P 		186.4
(3)
P 		95
avr 142.4
(1.2) 		109.6
(-1.9) 		98.1
(-3) 		160.9
(3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 624
1 2 3 4 5 6 range
A 108.1
(-3)
A 		122.9
(-2.8)
P 		163.6
(-2.3)
P 		265.9
(-1.1)
P 		536.7
(2.2)
P 		605
(3)
P 		497
B 136.2
(-2.9)
P 		140.9
(-2.8)
P 		124.2
(-3)
P 		256.2
(-1.7)
P 		607.4
(1.9)
P 		719.3
(3)
P 		595
C 95.1
(-3)
P 		169.8
(-2.2)
P 		174.3
(-2.1)
P 		284.5
(-0.9)
P 		466.8
(1.1)
P 		636.6
(3)
P 		542
avr 113.1
(-3) 		144.5
(-2.7) 		154
(-2.5) 		268.9
(-1.3) 		537
(1.7) 		653.6
(3) 		541
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 27
1 2 3 4 range
A 48.7
(3)
P 		29.2
(-1.4)
P 		27.3
(-1.8)
A 		21.9
(-3)
P 		27
B 46.9
(3)
P 		25.5
(-2.1)
A 		21.8
(-3)
P 		31.3
(-0.7)
P 		25
C 48.5
(3)
P 		26.1
(-3)
A 		33.5
(-1)
P 		31.4
(-1.6)
P 		22
avr 48
(3) 		26.9
(-3) 		27.5
(-2.8) 		28.2
(-2.6) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 248
1 2 3 4 5 6 range
A 19.9
(-3)
A 		43.7
(-2)
P 		35.6
(-2.3)
P 		67.4
(-1)
P 		161.9
(3)
P 		147.3
(2.4)
P 		142
B 47.4
(-2.6)
P 		46.9
(-2.6)
P 		30.2
(-3)
P 		67.9
(-2)
P 		246.8
(2.5)
P 		268.2
(3)
P 		238
C 35.3
(-3)
P 		51.8
(-2.4)
P 		44.4
(-2.7)
P 		57.2
(-2.3)
P 		151
(0.9)
P 		213.1
(3)
P 		178
avr 34.2
(-3) 		47.5
(-2.5) 		36.7
(-2.9) 		64.2
(-2) 		186.6
(2.2) 		209.5
(3) 		175
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172792_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10127
Sequence Type Exemplar sequence
Representative Public ID H02I12.8 NCBI
Target Description H02I12.8 /REP_DB=WormBase Gene ID /WP=CE16163 /TR=O45605 /GB=CAB07222.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Cytochrome P450
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069751(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069751 NCBI Caenorhabditis elegans CYtochrome P450 family member (cyp-31A2) (cyp-31A2) mRNA, complete cds. 11/11 None
H02I12.8 ENSEMBL cdna:known chromosome:CEL140:IV:11403932:11405967:1 gene:H02I12.8 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_068236 3/11 Cross Hyb Matching Probes A 
SNAP00000028585 3/11 Cross Hyb Matching Probes None
SNAP00000031438 2/11 Cross Hyb Matching Probes None
GENEFINDER00000031451 2/11 Cross Hyb Matching Probes None
SNAP00000036326 4/11 Cross Hyb Matching Probes None
GENEFINDER00000036327 3/11 Cross Hyb Matching Probes None
SNAP00000043800 3/11 Cross Hyb Matching Probes None
GENEFINDER00000043811 3/11 Cross Hyb Matching Probes None
Y17G9B.3 3/11 Cross Hyb Matching Probes A 
C01F6.3 2/11 Cross Hyb Matching Probes A 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11403948-11405559(+) 100.0 100.0
chrIV:4761056-4762644(+) 91.1 91.1
Public Domain and Genome References
Gene Title Cytochrome P450
Gene Symbol cyp-31A2
Ensembl H02I12.8
Entrez Gene 178065 Entrez gene
SwissProt O45605 EMBL-EBI
WormBase CE37719 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13905_AT cytochrome P450 97B3, putative (CYP97B3) at
ATH1-121501:245532_AT cytochrome P450 97B3, putative (CYP97B3) at
CANINE_2:CFAAFFX.11967.1.S1_AT similar to cytochrome P450, family 4, subfamily v, polypeptide 2 cfa
DROSOPHILA_2:1636716_AT Cytochrome P450-4c3 dm
DROSGENOME1:152045_AT Cytochrome P450-4c3 dm
HU35KSUBD:RC_AA450041_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.237642.1.A1_3P_X_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.237642.1.A1_3P_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.237642.0.S1_3P_X_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.237642.0.S1_3P_A_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133_PLUS_2:226745_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133B:226745_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133_PLUS_2:228391_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133B:228391_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95B:44074_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95C:54934_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95E:88338_AT cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95C:61444_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HU35KSUBD:RC_AA450201_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133_PLUS_2:235719_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133B:235719_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS2.381899.1.A1_3P_S_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.99237.0.A1_3P_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133_PLUS_2:1559441_S_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95E:78984_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133_PLUS_2:229959_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U133B:229959_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95C:53284_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
HG-U95E:90092_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
U133_X3P:HS.127317.0.A1_3P_AT Cytochrome P450, family 4, subfamily V, polypeptide 2 hs
MOE430A:1417071_S_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MOUSE430A_2:1417071_S_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MOUSE430_2:1417071_S_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MG-U74AV2:160611_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MOE430A:1417070_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MOUSE430A_2:1417070_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MOUSE430_2:1417070_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
MU19KSUBA:TC21779_AT cytochrome P450, family 4, subfamily v, polypeptide 3 mm
RG-U34B:RC_AA962978_AT cytochrome P450, family 4, subfamily v, polypeptide 3 (predicted) rn
RAE230B:1393906_AT cytochrome P450, family 4, subfamily v, polypeptide 3 (predicted) rn
RAT230_2:1393906_AT cytochrome P450, family 4, subfamily v, polypeptide 3 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4497 monooxygenase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92741 Hypothetical protein H02I12.8 [Caenorhabditis elegans] emb|CAB07222.3| Hypothetical protein H02I12.8 [Caenorhabditis elegans] ref|NP_502152.3| CYtochrome P450 family member (cyp-31A2) [Caenorhabditis elegans] 0.0
blast NP_500637 CYtochrome P450 family member (cyp-31A3) [Caenorhabditis elegans] gb|AAF60444.1| Cytochrome p450 family protein 31A3 [Caenorhabditis elegans] 0.0
blast CAE58606 Hypothetical protein CBG01773 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
p450 prf:1509339A Animalia; CYP2A6; hum; prf:1509339A; Homo sapiens; 1509339A 1.0E-126
Protein Domains
Database ID Description E-Value
Pfam IPR001128 EMBL-EBI Cytochrome P450 1.1E-125
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502152.3 1 2-21
H02I12.8 1 2-21
Sequence
Target Sequence 
>C. ELEGANS:172792_X_AT
cgcatttttggatcttcttctcgaaatggtgaaaagtggacaaatggacgaaacagatgt
tcaagcagaagttgacacatttatgtttgagggtcacgatacaacatctacaggattaat
gtgggcaattcatcttctgggaaatcatcctgaagttcagagaaaagttcaagcggaact
ggatgaagtaatgggcgacgatgaggacgtgactattgaacatctctccagaatgaaata
tctcgaatgtgcactaaaagaagctctgcgtctctttccatctgttccaattattacaag
agaactgagtgatgatcaagtcattggaggtgttaatattccaaaaggagtcacttttct
tctcaacctgtaccttgttcaccgtgatcctgctcaatggaaggatcctgatgtattcga
cccggatcgcttccttcctgaaaactcaattggtcgcaaatcattcgcctttatcccatt
ctcagctggaagccgtaactgcattggccaacgttttgcactcatggaagagaaggtcat
catggctcatttgttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGCATTTTTGGATCTTCTTCTCGAA 416 253 795 Antisense
GACGTGACTATTGAACATCTCTCCA 515 377 1000 Antisense
CTCTTTCCATCTGTTCCAATTATTA 141 231 1066 Antisense
TTCACCGTGATCCTGCTCAATGGAA 559 685 1172 Antisense
AAGGATCCTGATGTATTCGACCCGG 4 159 1195 Antisense
ATCGCTTCCTTCCTGAAAACTCAAT 207 37 1220 Antisense
AATTGGTCGCAAATCATTCGCCTTT 479 179 1242 Antisense
TATCCCATTCTCAGCTGGAAGCCGT 205 659 1266 Antisense
GGAAGCCGTAACTGCATTGGCCAAC 18 529 1282 Antisense
ATTGGCCAACGTTTTGCACTCATGG 413 3 1297 Antisense
GAAGGTCATCATGGCTCATTTGTTG 218 335 1326 Antisense
Sequence Source Affymetrix Proprietary Database