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[172738_x_at] cyclin B

Description Y43E12A.1 /REP_DB=WormBase Gene ID /WP=CE28122 /TR=O45926 /GB=CAA15975.2 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=cyclin B
Cluster 6grp_total > 88      4grp_total > 17      6grp_cgc > 59      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 242
1 2 3 4 range
A 94.8
(-3)
A 		129.4
(-2.1)
M 		172.1
(-0.9)
A 		318.2
(3)
P 		223
B 125
(-2.9)
A 		130.6
(-2.5)
A 		124
(-3)
A 		209.7
(3)
P 		86
C 76.4
(-3)
A 		128
(-0.9)
A 		133.4
(-0.6)
P 		220.8
(3)
P 		144
avr 98.7
(-3) 		129.3
(-1.8) 		143.2
(-1.2) 		249.6
(3) 		151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2811
1 2 3 4 5 6 range
A 124.8
(-2.9)
A 		79.6
(-3)
A 		165.4
(-2.8)
P 		333.3
(-2.4)
P 		1501.1
(0.6)
P 		2455
(3)
P 		2375
B 116.9
(-3)
M 		115.4
(-3)
A 		188.8
(-2.8)
P 		311.2
(-2.6)
P 		1506
(0.1)
P 		2833.2
(3)
P 		2718
C 93.5
(-3)
A 		158
(-2.9)
P 		145.8
(-2.9)
M 		256.7
(-2.6)
P 		1316.7
(-0.4)
P 		2890.9
(3)
P 		2797
avr 111.7
(-3) 		117.7
(-3) 		166.7
(-2.9) 		300.4
(-2.6) 		1441.3
(0.1) 		2726.4
(3) 		2615
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 34.5
(-0.9)
A 		28.1
(-3)
M 		45
(2.5)
A 		46.6
(3)
P 		19
B 39.9
(1.2)
A 		32.3
(-1.7)
A 		28.7
(-3)
A 		44.7
(3)
P 		16
C 25.3
(-3)
A 		36.8
(0.3)
A 		46.5
(3)
P 		37.2
(0.4)
P 		21
avr 33.2
(-2.5) 		32.4
(-3) 		40.1
(1.4) 		42.8
(3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1034
1 2 3 4 5 6 range
A 23
(-3)
A 		28.3
(-2.9)
A 		36
(-2.9)
P 		84.5
(-2.4)
P 		453
(1.5)
P 		597.7
(3)
P 		575
B 40.7
(-3)
M 		38.4
(-3)
A 		45.9
(-3)
P 		82.4
(-2.7)
P 		611.9
(0.4)
P 		1056.5
(3)
P 		1018
C 34.6
(-3)
A 		48.2
(-2.9)
P 		37.1
(-3)
M 		51.6
(-2.9)
P 		426.1
(-0.5)
P 		967.7
(3)
P 		933
avr 32.8
(-3) 		38.3
(-3) 		39.7
(-3) 		72.8
(-2.7) 		497
(0.3) 		874
(3) 		841
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172738_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8876
Sequence Type Exemplar sequence
Representative Public ID Y43E12A.1 NCBI
Target Description Y43E12A.1 /REP_DB=WormBase Gene ID /WP=CE28122 /TR=O45926 /GB=CAA15975.2 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=cyclin B
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069646(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069646 NCBI Caenorhabditis elegans CYclin B family member (cyb-2.1) (cyb-2.1) mRNA, complete cds. 11/11 None
SNAP00000002298 ENSEMBL cdna:SNAP chromosome:CEL140:IV:10985972:10987099:1 11/11 None
GENEFINDER00000002300 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:10982039:10987099:1 11/11 None
Y43E12A.1 ENSEMBL cdna:known chromosome:CEL140:IV:10985954:10987396:1 gene:Y43E12A.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_058896 8/11 Cross Hyb Matching Probes A 
SNAP00000031638 8/11 Cross Hyb Matching Probes None
GENEFINDER00000031646 8/11 Cross Hyb Matching Probes None
H31G24.4 8/11 Cross Hyb Matching Probes A 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:4114878-4116074(+) 96.29 96.29
chrIV:10985977-10987105(+) 100.0 100.0
Public Domain and Genome References
Gene Title cyclin B
Gene Symbol cyb-2.1
Ensembl Y43E12A.1
Entrez Gene 177994 Entrez gene
SwissProt O45926 EMBL-EBI
WormBase CE28122 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:17116_AT cyclin 1b (CYC1b) at
ATH1-121501:261159_S_AT cyclin, putative at
YEAST_2:1772627_AT B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
74 regulation of progression through cell cycle inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA15975 Hypothetical protein Y43E12A.1 [Caenorhabditis elegans] ref|NP_502047.1| CYclin B family member (cyb-2.1) [Caenorhabditis elegans] 1.0E-176
blast AAK21417 Cyclin b protein 2.2 [Caenorhabditis elegans] ref|NP_491297.1| H31G24.4 [Caenorhabditis elegans] 1.0E-162
blast AAK21417 Cyclin b protein 2.2 [Caenorhabditis elegans] ref|NP_491297.1| H31G24.4 [Caenorhabditis elegans] 1.0E-161
blast CAA15974 Hypothetical protein Y43E12A.2 [Caenorhabditis elegans] ref|NP_502046.2| Y43E12A.2 [Caenorhabditis elegans] 1.0E-132
blast CAA94384 Hypothetical protein ZC168.4 [Caenorhabditis elegans] ref|NP_501987.1| ZC168.4 [Caenorhabditis elegans] sp|Q10653|CCNB1_CAEEL G2/mitotic-specific cyclin B1 gb|AAA84394.1| cyclin B 1.0E-114
Protein Domains
Database ID Description E-Value
Pfam IPR004367 EMBL-EBI Cyclin, C-terminal 6.1E-22
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 8.4E-53
Pfam IPR004367 EMBL-EBI Cyclin, C-terminal 6.1E-22
Pfam IPR006671 EMBL-EBI Cyclin, N-terminal domain 8.4E-53
Sequence
Target Sequence 
>C. ELEGANS:172738_X_AT
aacgccttgaactttgacttgtcctgcccatcttcgcttgtcttcctccgctgtatttca
aaaactctcacagagaatgacgtcaatccaatcgataaggaagcgttctattatgtgcac
aatatctccaagtgtctcggagaactcgcattgctcgattcggtcatgtctacggttcca
aggtcgcacgttgccagtgcttcgatgatcatcactctcaatgttatcaccgttgatgga
attaatccgaagactgctgcatcgatgattcgcaaacaattaggagcctccaagcaagat
atttatgatgctatcgctctgctcgctcaagtcgcatataaaaacttcagacatcagaag
ctttgcgccattagagtaatatatttttacaaaatgtttactcagttttgttttcaggaa
aagtaccagtcgagcaagtttggacgagtatcctacttgatgaccgacga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AACGCCTTGAACTTTGACTTGTCCT 334 145 466 Antisense
TCTTCCTCCGCTGTATTTCAAAAAC 667 617 506 Antisense
GTGCACAATATCTCCAAGTGTCTCG 400 481 580 Antisense
GTGTCTCGGAGAACTCGCATTGCTC 54 487 597 Antisense
CGCATTGCTCGATTCGGTCATGTCT 436 253 612 Antisense
TCATGTCTACGGTTCCAAGGTCGCA 621 621 629 Antisense
CACGTTGCCAGTGCTTCGATGATCA 447 199 652 Antisense
GATCATCACTCTCAATGTTATCACC 299 421 672 Antisense
CTCTGCTCGCTCAAGTCGCATATAA 662 231 782 Antisense
GACATCAGAAGCTTTGCGCCATTAG 25 371 815 Antisense
GAGTATCCTACTTGATGACCGACGA 104 399 911 Antisense
Sequence Source Affymetrix Proprietary Database