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[172069_x_at] cathepsin protease

Description g675493 /REP_DB=GenBank Identifier /GB=L39890.1 /PROTEIN_GB=AAA98788.1 /CHR=5 /FEA=Mapped Transcript /DEF=cathepsin B-like cysteine proteinase
Cluster 6grp_highest_10_10 > 12      6grp_high1_10_10 > 37      4grp_high_8_8 > 49      6grp_highest_nonorm > 71      6grp_total > 08      4grp_total > 63      6grp_cgc > 0      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 736
1 2 3 4 range
A 615.4
(3)
P 		313.2
(-0.7)
P 		390.5
(0.2)
P 		127.9
(-3)
A 		488
B 821.3
(3)
P 		309.5
(-1.3)
P 		355.3
(-0.9)
P 		111.4
(-3)
P 		710
C 669.9
(3)
P 		297.6
(-0.8)
P 		371.2
(-0.1)
P 		85.4
(-3)
P 		585
avr 702.2
(3) 		306.8
(-1) 		372.3
(-0.3) 		108.2
(-3) 		594

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 315
1 2 3 4 5 6 range
A 519.3
(3)
P 		263.1
(-2.7)
P 		425.6
(0.9)
P 		372.2
(-0.3)
P 		248.4
(-3)
P 		341
(-0.9)
P 		271
B 445.6
(3)
P 		258
(-3)
P 		391.6
(1.3)
P 		411
(1.9)
P 		323
(-0.9)
P 		355.7
(0.1)
P 		188
C 423.4
(3)
P 		250.3
(-1.7)
P 		395.3
(2.2)
P 		411.1
(2.7)
P 		204.5
(-3)
P 		412.1
(2.7)
P 		219
avr 462.8
(3) 		257.1
(-3) 		404.2
(1.3) 		398.1
(1.1) 		258.6
(-3) 		369.6
(0.3) 		206
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 248
1 2 3 4 range
A 224.1
(3)
P 		68
(-1.6)
P 		102.1
(-0.6)
P 		18.7
(-3)
A 		205
B 261.9
(3)
P 		76.4
(-1.7)
P 		82.3
(-1.5)
P 		23.7
(-3)
P 		238
C 221.8
(3)
P 		85.5
(-0.9)
P 		129.4
(0.3)
P 		14.4
(-3)
P 		207
avr 235.9
(3) 		76.6
(-1.4) 		104.6
(-0.6) 		18.9
(-3) 		217

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 91
1 2 3 4 5 6 range
A 95.7
(3)
P 		93.6
(2.4)
P 		92.7
(2.1)
P 		94.4
(2.6)
P 		75
(-3)
P 		83
(-0.7)
P 		21
B 155
(3)
P 		85.9
(-3)
P 		95.1
(-2.2)
P 		108.9
(-1)
P 		131.2
(0.9)
P 		132.6
(1.1)
P 		69
C 156.9
(3)
P 		76.4
(-2.3)
P 		100.6
(-0.7)
P 		82.7
(-1.9)
P 		66.2
(-3)
P 		137.9
(1.7)
P 		91
avr 135.9
(3) 		85.3
(-3) 		96.1
(-1.7) 		95.3
(-1.8) 		90.8
(-2.3) 		117.8
(0.9) 		51
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172069_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19931
Sequence Type Exemplar sequence
Representative Public ID 675493 NCBI
Target Description g675493 /REP_DB=GenBank Identifier /GB=L39890.1 /PROTEIN_GB=AAA98788.1 /CHR=5 /FEA=Mapped Transcript /DEF=cathepsin B-like cysteine proteinase
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074389(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074389 NCBI Caenorhabditis elegans Cysteine PRotease related family member (cpr-3) (cpr-3) mRNA, complete cds. 11/11 A 
T10H4.12 ENSEMBL cdna:known chromosome:CEL140:V:15299436:15301262:-1 gene:T10H4.12 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15299435-15301262(-) 100.0 100.0
Public Domain and Genome References
Gene Title cathepsin protease
Gene Symbol cpr-3
Ensembl T10H4.12
Entrez Gene 180033 Entrez gene
SwissProt P43507 EMBL-EBI
WormBase CE27590 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB61032 Hypothetical protein T10H4.12 [Caenorhabditis elegans] emb|CAB61024.2| Hypothetical protein T10H4.12 [Caenorhabditis elegans] ref|NP_506790.1| Cysteine PRotease related family member (cpr-3) [Caenorhabditis elegans] sp|P43507|CPR3_CAEEL Cathepsin B-like cysteine proteinase 3 precursor (Cysteine protease-related 3) gb|AAA98788.1| cathepsin B-like cysteine proteinase gb|AAA98782.1| cathepsin B-like cysteine proteinase 0.0
blast T24819 hypothetical protein T10H4.12 - Caenorhabditis elegans 1.0E-171
blast CAE71663 Hypothetical protein CBG18635 [Caenorhabditis briggsae] 1.0E-146
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 6.2E-107
Sequence
Target Sequence 
>C. ELEGANS:172069_X_AT
atggagcttctgcctacaaagtcaccactacgaaatccgtcaccgaaattcaaactgaaa
tctaccattacggacctgtggaggcttcatacaaagtctacgaggatttttatcattata
aatcaggagtttatcactatacttccggaaagcttgttggaggtcacgcggttaaaatta
tcggctggggagttgaaaacggagtggactactggctgattgcaaattcctggggcacca
gtttcggcgaaaaggggttcttcaaaattcgccgtggaacaaatgaatgtcaaattgaag
gaaacgtggtagctggaattgcaaaattgggaacgcactcggaaacgtatgaagacgatg
gcggtgcagcgacctcgtgtagttttattatgtgtacattgatggtgctgacgtattatt
tcgtgtagaaaagagaagataacggctcttcttttatcgattaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGGAGCTTCTGCCTACAAAGTCAC 140 53 758 Antisense
AAGTCACCACTACGAAATCCGTCAC 704 155 776 Antisense
TGAAATCTACCATTACGGACCTGTG 433 571 813 Antisense
CGGACCTGTGGAGGCTTCATACAAA 428 243 828 Antisense
GAGTTTATCACTATACTTCCGGAAA 54 397 884 Antisense
AAGCTTGTTGGAGGTCACGCGGTTA 332 151 907 Antisense
GGAGTGGACTACTGGCTGATTGCAA 86 515 958 Antisense
GATTGCAAATTCCTGGGGCACCAGT 528 427 975 Antisense
TGAAGACGATGGCGGTGCAGCGACC 56 575 1107 Antisense
GCAGCGACCTCGTGTAGTTTTATTA 183 309 1123 Antisense
TAACGGCTCTTCTTTTATCGATTAA 594 637 1197 Antisense
Sequence Source GenBank