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[172058_x_at]

Description g8037936 /REP_DB=GenBank Identifier /GB=AF255956.1 /PROTEIN_GB=AAF71543.1 /CHR=4 /FEA=Mapped Transcript /DEF=calcium-calmodulin-dependent protein kinase IIisoform H
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 05      4grp_highest_8_8 > 58      4grp_high_8_8 > 33      6grp_highest_nonorm > 30      6grp_total > 15      4grp_total > 46      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 745
1 2 3 4 range
A 1195.7
(3)
P 		745.7
(-0.7)
P 		475.4
(-3)
P 		672.3
(-1.4)
P 		720
B 1220
(3)
P 		697.7
(-1.7)
P 		553.1
(-3)
P 		670.6
(-1.9)
P 		667
C 1163.5
(3)
P 		779.1
(-1.1)
P 		601.2
(-3)
P 		640.3
(-2.6)
P 		562
avr 1193.1
(3) 		740.8
(-1.2) 		543.2
(-3) 		661.1
(-1.9) 		650

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 858
1 2 3 4 5 6 range
A 1111.3
(3)
P 		905.2
(0.9)
P 		639.9
(-1.8)
P 		526.8
(-3)
P 		774.7
(-0.5)
P 		561.8
(-2.6)
P 		585
B 1080.1
(2.8)
P 		1102.8
(3)
P 		995.6
(1.8)
P 		714.4
(-1.3)
P 		566.5
(-2.9)
P 		556.7
(-3)
P 		546
C 1384.9
(3)
P 		1113.3
(1)
P 		706.9
(-1.9)
P 		597.1
(-2.7)
P 		623.4
(-2.5)
P 		559
(-3)
P 		826
avr 1192.1
(3) 		1040.4
(1.6) 		780.8
(-0.9) 		612.8
(-2.5) 		654.9
(-2.1) 		559.2
(-3) 		633
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 337
1 2 3 4 range
A 435.3
(3)
P 		161.9
(-1.9)
P 		124.3
(-2.5)
P 		98.4
(-3)
P 		337
B 389.1
(3)
P 		172.3
(-2)
P 		128.2
(-3)
P 		142.9
(-2.7)
P 		261
C 385.2
(3)
P 		224
(-0.5)
P 		209.5
(-0.8)
P 		108
(-3)
P 		277
avr 403.2
(3) 		186.1
(-1.5) 		154
(-2.2) 		116.4
(-3) 		287

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 393
1 2 3 4 5 6 range
A 204.9
(-0.7)
P 		321.9
(3)
P 		139.4
(-2.8)
P 		133.6
(-3)
P 		233.8
(0.2)
P 		136.8
(-2.9)
P 		188
B 375.8
(3)
P 		367.1
(2.7)
P 		241.8
(-1.3)
P 		189.2
(-3)
P 		230.2
(-1.7)
P 		207.6
(-2.4)
P 		187
C 513.3
(3)
P 		339.7
(0.4)
P 		179.9
(-2.1)
P 		120.1
(-3)
P 		201.7
(-1.8)
P 		187.1
(-2)
P 		393
avr 364.7
(3) 		342.9
(2.4) 		187
(-1.9) 		147.6
(-3) 		221.9
(-0.9) 		177.2
(-2.2) 		217
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172058_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19841
Sequence Type Exemplar sequence
Representative Public ID 8037936 NCBI
Target Description g8037936 /REP_DB=GenBank Identifier /GB=AF255956.1 /PROTEIN_GB=AAF71543.1 /CHR=4 /FEA=Mapped Transcript /DEF=calcium-calmodulin-dependent protein kinase IIisoform H
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028125(11), NM_001028132(9), NM_001028122(11), NM_001028128(11), NM_001028127(11), NM_001028124(9), NM_001028126(11), NM_001028129(11), NM_001028130(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028125 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028132 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 9/11 None
NM_001028122 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028128 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028127 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028124 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 9/11 None
NM_001028126 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028129 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
NM_001028130 NCBI Caenorhabditis elegans UNCoordinated family member (unc-43) (unc-43) mRNA, complete cds. 11/11 None
K11E8.1d ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340517:-1 gene:K11E8.1 11/11 A 
K11E8.1l ENSEMBL cdna:known chromosome:CEL140:IV:10324241:10340528:-1 gene:K11E8.1 9/11 A 
K11E8.1e ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1h ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1c ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 9/11 A 
K11E8.1a ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1f ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1g ENSEMBL cdna:known chromosome:CEL140:IV:10324967:10340140:-1 gene:K11E8.1 11/11 A 
K11E8.1i ENSEMBL cdna:known chromosome:CEL140:IV:10328371:10340140:-1 gene:K11E8.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_001028131 8/11 Cross Hyb Matching Probes None
NM_001028133 1/11 Cross Hyb Matching Probes None
SNAP00000001604 8/11 Cross Hyb Matching Probes None
GENEFINDER00000001606 8/11 Cross Hyb Matching Probes None
GENEFINDER00000001607 1/11 Cross Hyb Matching Probes None
K11E8.1k 8/11 Cross Hyb Matching Probes A 
K11E8.1m 1/11 Cross Hyb Matching Probes A 
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
177921 12 9 NM_001028122 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028123 187759_s_at (11), 193459_s_at (11)
NM_001028124 172058_x_at (9), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028125 172058_x_at (11), 175821_s_at (11), 175824_s_at (11), 187759_s_at (11), 193459_s_at (11)
NM_001028126 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11)
NM_001028127 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028128 172058_x_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028129 172058_x_at (11), 175820_s_at (11), 175821_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028130 172058_x_at (11), 173423_at (11), 193459_s_at (11)
NM_001028131 175821_s_at (11), 175824_s_at (11), 193459_s_at (11), 193463_s_at (11)
NM_001028132 172058_x_at (9), 175821_s_at (11), 175824_s_at (11), 193459_s_at (11)
NM_001028133 175821_s_at (11), 193463_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:10329062-10340146(-) 100.0 100.0
Public Domain and Genome References
Ensembl K11E8.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAC42326 Hypothetical protein K11E8.1d [Caenorhabditis elegans] emb|CAC42364.1| Hypothetical protein K11E8.1d [Caenorhabditis elegans] ref|NP_001023296.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAD53949.1| calcium/calmodulin dependent protein kinase II [Caenorhabditis elegans] 0.0
blast CAC42323 Hypothetical protein K11E8.1g [Caenorhabditis elegans] emb|CAC42361.1| Hypothetical protein K11E8.1g [Caenorhabditis elegans] ref|NP_001023299.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63320.1| calcium/calmodulin-dependent protein kinase II isoform B [Caenorhabditis elegans] 0.0
blast CAC42327 Hypothetical protein K11E8.1f [Caenorhabditis elegans] emb|CAC42365.1| Hypothetical protein K11E8.1f [Caenorhabditis elegans] ref|NP_001023298.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] gb|AAF63323.1| calcium/calmodulin-dependent protein kinase II isoform E [Caenorhabditis elegans] 0.0
blast CAA94242 Hypothetical protein K11E8.1a [Caenorhabditis elegans] emb|CAC42358.1| Hypothetical protein K11E8.1a [Caenorhabditis elegans] ref|NP_001023293.1| UNCoordinated family member (unc-43) [Caenorhabditis elegans] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 7.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-67
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-68
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-137
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-138
hanks 2.1.5 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; DmCamKII 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.3E-97
Sequence
Target Sequence 
>C. ELEGANS:172058_X_AT
aaagcttgccgattttggtcttgcaatcgaagtgaacgatagtgaagcatggcacggatt
tgctggaactccaggatacttgtcgccagaagttctcaagaaggatccatactcaaagcc
agttgatatctgggcttgtggtgtcattctgtacatccttcttgttggatacccaccatt
ctgggatgaggaccaacaccgtttatacgcacaaatcaaggctggagcctatgattaccc
gagccccgaatgggatacggtgaccccggaggcaaaaagcctcatcgacagcatgctgac
ggtgaacccaaagaagcgtatcaccgctgatcaggccttgaaagtcccatggatttgcaa
tcgcgaacgcgttgcatcagctatccacagacaggatactgttgactgcttgaagaaatt
caatgcaaggcggaagttgaagggtgccatcctcacgacgatgattgccactcgaaacct
atcaaatttaggtcgcaatctgctaaacaaaaaagagcaaggaccaccatcgacaatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAGCTTGCCGATTTTGGTCTTGCA 563 123 465 Antisense
TGGAACTCCAGGATACTTGTCGCCA 575 547 528 Antisense
TGTGGTGTCATTCTGTACATCCTTC 600 555 601 Antisense
GAGGACCAACACCGTTTATACGCAC 488 401 652 Antisense
GCTGGAGCCTATGATTACCCGAGCC 99 295 685 Antisense
GAAGCGTATCACCGCTGATCAGGCC 380 341 777 Antisense
GATCAGGCCTTGAAAGTCCCATGGA 293 421 793 Antisense
AATCGCGAACGCGTTGCATCAGCTA 49 165 823 Antisense
GAAGTTGAAGGGTGCCATCCTCACG 445 337 897 Antisense
ATCCTCACGACGATGATTGCCACTC 530 39 913 Antisense
AGAGCAAGGACCACCATCGACAATC 583 69 978 Antisense
Sequence Source GenBank