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[172057_x_at] aryl hydrocarbon receptor nuclear translocator

Description g2828111 /REP_DB=GenBank Identifier /GB=AF039569.1 /PROTEIN_GB=AAB99999.1 /CHR=1 /FEA=Mapped Transcript /DEF=aryl hydrocarbon receptor nuclear translocatorortholog AHA-1
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 17      4grp_highest_8_8 > 53      4grp_high_8_8 > 09      6grp_highest_nonorm > 40      6grp_total > 16      4grp_total > 23      6grp_highest_sub > De      6grp_cgc > 12      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 513
1 2 3 4 range
A 634.3
(3)
P 		285.6
(-3)
P 		293.9
(-2.9)
P 		467.7
(0.1)
P 		349
B 569.3
(3)
P 		205.6
(-2.8)
P 		193.4
(-3)
P 		556.8
(2.8)
P 		376
C 705.9
(3)
P 		249.5
(-3)
P 		320.5
(-2.1)
P 		541.7
(0.8)
P 		456
avr 636.5
(3) 		246.9
(-3) 		269.3
(-2.7) 		522.1
(1.2) 		390

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 574
1 2 3 4 5 6 range
A 864.7
(3)
P 		563.1
(-1.3)
P 		506.5
(-2.1)
P 		441.3
(-3)
P 		466
(-2.6)
P 		476.7
(-2.5)
P 		423
B 878.3
(3)
P 		625.8
(-0.2)
P 		399.4
(-3)
P 		534.9
(-1.3)
P 		538.6
(-1.3)
P 		483.9
(-1.9)
P 		479
C 903.7
(3)
P 		674.2
(0.6)
P 		493.2
(-1.3)
P 		436.9
(-1.9)
P 		330.1
(-3)
P 		439
(-1.9)
P 		574
avr 882.2
(3) 		621
(-0.6) 		466.4
(-2.7) 		471
(-2.6) 		444.9
(-3) 		466.5
(-2.7) 		437
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 189
1 2 3 4 range
A 231
(3)
P 		62
(-3)
P 		76.8
(-2.5)
P 		68.5
(-2.8)
P 		169
B 181.5
(3)
P 		50.8
(-2.7)
P 		44.8
(-3)
P 		118.7
(0.2)
P 		137
C 233.7
(3)
P 		71.7
(-3)
P 		111.7
(-1.5)
P 		91.3
(-2.3)
P 		162
avr 215.4
(3) 		61.5
(-3) 		77.8
(-2.4) 		92.8
(-1.8) 		154

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 247
1 2 3 4 5 6 range
A 159.4
(0.3)
P 		200.3
(3)
P 		110.3
(-3)
P 		111.9
(-2.9)
P 		140.6
(-1)
P 		116.1
(-2.6)
P 		90
B 305.6
(3)
P 		208.3
(0.2)
P 		97
(-3)
P 		141.7
(-1.7)
P 		218.8
(0.5)
P 		180.4
(-0.6)
P 		209
C 335
(3)
P 		205.7
(-0.1)
P 		125.5
(-2.1)
P 		87.9
(-3)
P 		106.8
(-2.5)
P 		147
(-1.6)
P 		247
avr 266.7
(3) 		204.8
(0.6) 		110.9
(-3) 		113.8
(-2.9) 		155.4
(-1.3) 		147.8
(-1.6) 		156
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 172057_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19647
Sequence Type Exemplar sequence
Representative Public ID 2828111 NCBI
Target Description g2828111 /REP_DB=GenBank Identifier /GB=AF039569.1 /PROTEIN_GB=AAB99999.1 /CHR=1 /FEA=Mapped Transcript /DEF=aryl hydrocarbon receptor nuclear translocatorortholog AHA-1
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060286(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060286 NCBI Caenorhabditis elegans Aryl Hydrocarbon receptor Associated protein family member (aha-1) (aha-1) mRNA, complete cds. 11/11 A 
SNAP00000000662 ENSEMBL cdna:SNAP chromosome:CEL140:I:10202280:10205111:-1 9/11 None
GENEFINDER00000000677 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:10202280:10205111:-1 9/11 None
C25A1.11 ENSEMBL cdna:known chromosome:CEL140:I:10202047:10205121:-1 gene:C25A1.11 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10201976-10205050(-) 96.5 100.0
Public Domain and Genome References
Gene Title aryl hydrocarbon receptor nuclear translocator
Gene Symbol aha-1
Ensembl C25A1.11
Entrez Gene 172889 Entrez gene
SwissProt O02219 EMBL-EBI
WormBase CE08377 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.19026.1.S1_S_AT similar to Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta) cfa
DROSOPHILA_2:1635754_AT tango dm
DROSGENOME1:154596_AT tango dm
CHICKEN:GGA.4290.1.S1_AT aryl hydrocarbon receptor nuclear translocator gga
CHICKEN:GGA.8458.1.A1_AT aryl hydrocarbon receptor nuclear translocator gga
HG-U133A:218221_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133A_2:218221_AT aryl hydrocarbon receptor nuclear translocator hs
HG-FOCUS:218221_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:218221_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:233724_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133B:233724_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:210828_S_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133A:210828_S_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133A_2:210828_S_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:218222_X_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133A_2:218222_X_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133A:218222_X_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95AV2:35967_AT aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBB:RC_R14892_AT aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBC:RC_W47196_AT aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBC:RC_F04564_AT aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBD:RC_R44761_AT aryl hydrocarbon receptor nuclear translocator hs
HUGENEFL:M69238_AT aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:G4502230_3P_A_AT aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:G2702318_3P_A_AT aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:HS.306446.0.S1_3P_X_AT aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:HS.166172.2.S1_3P_AT aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:HS.166172.0.A2_3P_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:230619_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133B:230619_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95AV2:35968_S_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95B:52811_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95B:54673_S_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95C:63275_I_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U95C:63721_AT aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:231016_S_AT Aryl hydrocarbon receptor nuclear translocator hs
HG-U133B:231016_S_AT Aryl hydrocarbon receptor nuclear translocator hs
HG-U133_PLUS_2:233714_AT Aryl hydrocarbon receptor nuclear translocator hs
HG-U133B:233714_AT Aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBC:RC_T67552_AT Aryl hydrocarbon receptor nuclear translocator hs
HU35KSUBD:RC_N55484_AT Aryl hydrocarbon receptor nuclear translocator hs
U133_X3P:HS.166172.3.S1_3P_AT Aryl hydrocarbon receptor nuclear translocator hs
MOUSE430_2:1421721_A_AT aryl hydrocarbon receptor nuclear translocator mm
MOE430A:1421721_A_AT aryl hydrocarbon receptor nuclear translocator mm
MOUSE430A_2:1421721_A_AT aryl hydrocarbon receptor nuclear translocator mm
MOUSE430_2:1425064_AT aryl hydrocarbon receptor nuclear translocator mm
MOE430A:1425064_AT aryl hydrocarbon receptor nuclear translocator mm
MOUSE430A_2:1425064_AT aryl hydrocarbon receptor nuclear translocator mm
MU11KSUBA:U10325_S_AT aryl hydrocarbon receptor nuclear translocator mm
MG-U74AV2:97185_AT aryl hydrocarbon receptor nuclear translocator mm
MG-U74AV2:92529_S_AT aryl hydrocarbon receptor nuclear translocator mm
MG-U74BV2:115047_AT aryl hydrocarbon receptor nuclear translocator mm
MG-U74BV2:108908_AT aryl hydrocarbon receptor nuclear translocator mm
MOE430B:1437042_AT aryl hydrocarbon receptor nuclear translocator mm
MOUSE430_2:1437042_AT aryl hydrocarbon receptor nuclear translocator mm
MOE430B:1419996_S_AT aryl hydrocarbon receptor nuclear translocator mm
MOUSE430_2:1419996_S_AT aryl hydrocarbon receptor nuclear translocator mm
MU19KSUBA:TC17530_AT Aryl hydrocarbon receptor nuclear translocator, mRNA (cDNA clone MGC:11512 IMAGE:3964932) mm
RAE230A:1369244_AT aryl hydrocarbon receptor nuclear translocator rn
RAT230_2:1369244_AT aryl hydrocarbon receptor nuclear translocator rn
RT-U34:U61184_AT aryl hydrocarbon receptor nuclear translocator rn
RG-U34A:U61184_AT aryl hydrocarbon receptor nuclear translocator rn
RG-U34A:U08986_S_AT aryl hydrocarbon receptor nuclear translocator rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
7165 signal transduction inferred from electronic annotation QuickGO AmiGO
9410 response to xenobiotic stimulus inferred from direct assay QuickGO AmiGO
45449 regulation of transcription inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
4871 signal transducer activity inferred from electronic annotation QuickGO AmiGO
4871 signal transducer activity inferred from sequence similarity QuickGO AmiGO
5061 aryl hydrocarbon receptor nuclear translocator activity inferred from sequence similarity QuickGO AmiGO
3677 DNA binding inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02764 Hypothetical protein C25A1.11 [Caenorhabditis elegans] ref|NP_492687.1| Aryl Hydrocarbon receptor Associated protein family member (aha-1) [Caenorhabditis elegans] 0.0
blast AAB99999 aryl hydrocarbon receptor nuclear translocator ortholog AHA-1 [Caenorhabditis elegans] 0.0
blast CAE66847 Hypothetical protein CBG12219 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000014 EMBL-EBI PAS domain 3.0E-8
Pfam IPR001092 EMBL-EBI Basic helix-loop-helix dimerization domain bHLH 1.0E-15
Pfam IPR000014 EMBL-EBI PAS domain 3.0E-8
Pfam IPR001092 EMBL-EBI Basic helix-loop-helix dimerization domain bHLH 1.0E-15
Sequence
Target Sequence 
>C. ELEGANS:172057_X_AT
gtggaatcttgcacatccagcagatgagaagacccttcaagactcatttgtggctctttt
aagtgaccaaccaatgagaataaatattcgagtacgtaccagtactgattacattccatg
tactgtgtctgcatacaaattcatgaatccatactcggaacagttcgaatacgtggttgc
aacacatcaaattgctccacaagaagatattaataattgggtcactgcaccaactgttcc
tcaacctcaagccagtgaatttggagagctcggcggtgctccaagtgctgtggattacgg
acaatcgagtagtggaggatggagacctgaagctcaaggagcaccacaggcacaatggca
atgggacccgatgaatggatataaccagtgattataatttctagaaattgatatattttt
ttttgaagcctattccaatgattctcatttctatctacttcttg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGAATCTTGCACATCCAGCAGAT 425 491 986 Antisense
GACCCTTCAAGACTCATTTGTGGCT 671 381 1016 Antisense
GGCTCTTTTAAGTGACCAACCAATG 106 535 1037 Antisense
TACATTCCATGTACTGTGTCTGCAT 395 645 1095 Antisense
AATTGGGTCACTGCACCAACTGTTC 142 177 1200 Antisense
TTCCTCAACCTCAAGCCAGTGAATT 349 699 1222 Antisense
AATTTGGAGAGCTCGGCGGTGCTCC 195 175 1243 Antisense
GCGGTGCTCCAAGTGCTGTGGATTA 503 293 1258 Antisense
GGCACAATGGCAATGGGACCCGATG 318 535 1334 Antisense
GAAGCCTATTCCAATGATTCTCATT 334 345 1410 Antisense
GATTCTCATTTCTATCTACTTCTTG 14 433 1425 Antisense
Sequence Source GenBank