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[171893_x_at] DNA replication licensing factor MCM3

Description CEC9093_rc /REP_DB=TREMBL Accession /GB=C10909 /FEA=Transcript Cluster /DEF=C.elegans cDNA clone yk159f12 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 97      6grp_high1_10_10 > 78      4grp_highest_8_8 > 25      4grp_high_8_8 > 60      6grp_highest_nonorm > 93      6grp_total > 79      4grp_total > 60      6grp_highest_sub > Cu      6grp_cgc > 39      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 258
1 2 3 4 range
A 341.2
(2.8)
P
310.6
(1.7)
P
346
(3)
P
182.5
(-3)
P
164
B 255.7
(0.2)
P
283.4
(0.9)
P
366.1
(3)
P
132.5
(-3)
P
234
C 328.2
(1.4)
P
355.6
(2.1)
P
390
(3)
P
151.1
(-3)
P
239
avr 308.4
(1.3)
316.5
(1.6)
367.4
(3)
155.4
(-3)
212

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 558
1 2 3 4 5 6 range
A 242.2
(-1.6)
P
209.2
(-2.1)
P
151.2
(-3)
P
177.7
(-2.6)
P
379.1
(0.5)
P
542.4
(3)
P
391
B 323
(-1.4)
P
226.6
(-2.5)
P
185.4
(-3)
P
208.5
(-2.7)
P
374.7
(-0.8)
P
700
(3)
P
515
C 357.5
(-0.8)
P
286.4
(-1.6)
P
156.9
(-3)
P
260.3
(-1.9)
P
427.4
(-0.1)
P
709.5
(3)
P
553
avr 307.6
(-1.2)
240.7
(-2.1)
164.5
(-3)
215.5
(-2.4)
393.7
(-0.2)
650.6
(3)
486
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 110
1 2 3 4 range
A 124.2
(3)
P
67.4
(-0.5)
P
90.5
(0.9)
P
26.7
(-3)
P
98
B 81.5
(2.7)
P
70
(1.4)
P
84.8
(3)
P
28.2
(-3)
P
57
C 108.7
(1.5)
P
102.2
(1.2)
P
135.9
(3)
P
25.5
(-3)
P
110
avr 104.8
(3)
79.9
(1.1)
103.7
(2.9)
26.8
(-3)
78

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 228
1 2 3 4 5 6 range
A 44.6
(-2.3)
P
74.4
(-0.5)
P
32.9
(-3)
P
45.1
(-2.3)
P
114.4
(1.9)
P
132.1
(3)
P
99
B 112.4
(-1.1)
P
75.4
(-2.2)
P
45
(-3)
P
55.2
(-2.7)
P
152.2
(-0)
P
261
(3)
P
216
C 132.5
(-0.2)
P
87.4
(-1.6)
P
39.9
(-3)
P
52.3
(-2.6)
P
138.3
(-0)
P
237.5
(3)
P
198
avr 96.5
(-1)
79.1
(-1.6)
39.3
(-3)
50.9
(-2.6)
135
(0.4)
210.2
(3)
171
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 171893_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.27841
Sequence Type Exemplar sequence
Representative Public ID CEC9093 NCBI
Target Description CEC9093_rc /REP_DB=TREMBL Accession /GB=C10909 /FEA=Transcript Cluster /DEF=C.elegans cDNA clone yk159f12 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Transcript Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074305
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
C25D7.6.2 ENSEMBL cdna:known chromosome:CEL140:V:15059306:15062187:-1 gene:C25D7.6 A 
GENEFINDER00000019719 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15059546:15062180:-1 None
C25D7.6.1 ENSEMBL cdna:known chromosome:CEL140:V:15059306:15062314:-1 gene:C25D7.6 A 
NM_074305 NCBI Caenorhabditis elegans yeast MCM (licensing factor) related family member (mcm-3) (mcm-3) mRNA, complete cds. A 
SNAP00000019710 ENSEMBL cdna:SNAP chromosome:CEL140:V:15059546:15062180:-1 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15059380-15059725(-) 96.33 96.33
Public Domain and Genome References
Gene Title DNA replication licensing factor MCM3
Gene Symbol mcm-3
Ensembl C25D7.6
Entrez Gene 180010 Entrez gene
SwissProt Q9XVR7 EMBL-EBI
WormBase CE08392 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:16823_AT DNA replication licensing factor, putative at
ATH1-121501:248891_AT DNA replication licensing factor, putative at
CANINE_2:CFAAFFX.4185.1.S1_AT similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3) cfa
CANINE_2:CFAAFFX.4188.1.S1_AT similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3) cfa
CANINE_2:CFAAFFX.4188.1.S1_S_AT similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3) cfa
CANINE_2:CFAAFFX.4190.1.S1_AT similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3) cfa
DROSOPHILA_2:1635234_AT Minichromosome maintenance 3 dm
DROSGENOME1:153592_AT Minichromosome maintenance 3 dm
CHICKEN:GGAAFFX.11455.1.S1_S_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) gga
HG-U133_PLUS_2:201555_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HG-U133A:201555_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HG-FOCUS:201555_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HG-U133A_2:201555_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HUGENEFL:X62153_S_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HUGENEFL:D38073_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
U133_X3P:G6631094_3P_X_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
U133_X3P:G6631094_3P_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
U133_X3P:201555_3P_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
HG-U95AV2:33252_AT MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) hs
MOUSE430_2:1426652_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOUSE430A_2:1426652_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOE430A:1426652_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOUSE430A_2:1426653_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOUSE430_2:1426653_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOE430A:1426653_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOE430A:1420028_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOUSE430A_2:1420028_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOUSE430_2:1420028_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MU11KSUBB:MSA.42771.0_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MU11KSUBB:X62154_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MG-U74AV2:100062_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MG-U74AV2:160496_S_AT minichromosome maintenance deficient 3 (S. cerevisiae) mm
MOE430A:1420029_AT Minichromosome maintenance deficient 3 (S. cerevisiae), mRNA (cDNA clone MGC:30531 IMAGE:5007886) mm
MOUSE430A_2:1420029_AT Minichromosome maintenance deficient 3 (S. cerevisiae), mRNA (cDNA clone MGC:30531 IMAGE:5007886) mm
MOUSE430_2:1420029_AT Minichromosome maintenance deficient 3 (S. cerevisiae), mRNA (cDNA clone MGC:30531 IMAGE:5007886) mm
MU19KSUBB:TC33816_AT Minichromosome maintenance deficient 3 (S. cerevisiae), mRNA (cDNA clone MGC:30531 IMAGE:5007886) mm
RG-U34C:RC_AI178684_AT minichromosome maintenance deficient 3 (S. cerevisiae) (predicted) rn
RAE230A:1372406_AT minichromosome maintenance deficient 3 (S. cerevisiae) (predicted) rn
RAT230_2:1372406_AT minichromosome maintenance deficient 3 (S. cerevisiae) (predicted) rn
YEAST_2:1775015_AT Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6270 DNA replication initiation inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
166 nucleotide binding inferred from electronic annotation QuickGO AmiGO
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
8094 DNA-dependent ATPase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02770 Hypothetical protein C25D7.6 [Caenorhabditis elegans] ref|NP_506706.1| yeast MCM (licensing factor) related family member (mcm-3) [Caenorhabditis elegans] 0.0
blast CAE66328 Hypothetical protein CBG11579 [Caenorhabditis briggsae] 0.0
blast CAI11688 MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like [Danio rerio] ref|XP_702523.1| PREDICTED: hypothetical protein XP_697431 [Danio rerio] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001208 EMBL-EBI MCM 1.0E-126
Sequence
Target Sequence
>C. ELEGANS:171893_X_AT
attatcacagacagtgttcacactcaagccggatcacacaagttcactgaggatgagctg
aaggctggatacgaacaattggggagcgataacgctgcaatgattgccgaagataagatc
actctcatctaatttcctgctggaagctggaacataagccccgttttcttttcgatctct
caatcgaatnattatnttatcgnnnnnnncacctgattatcattcctatttcat


BLASTn GenBank NR
Note: "n"'s represent regions that are not probed by the probe sequences.
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
ATTATCACAGACAGTGTTCACACTC 351 13 15 Antisense
AGTGTTCACACTCAAGCCGGATCAC 659 59 27 Antisense
GCCGGATCACACAAGTTCACTGAGG 379 283 42 Antisense
GAGCTGAAGGCTGGATACGAACAAT 464 387 69 Antisense
CGAACAATTGGGGAGCGATAACGCT 505 251 86 Antisense
GAGCGATAACGCTGCAATGATTGCC 274 387 98 Antisense
TGCCGAAGATAAGATCACTCTCATC 418 585 119 Antisense
ACTCTCATCTAATTTCCTGCTGGAA 315 99 135 Antisense
GGAAGCTGGAACATAAGCCCCGTTT 657 529 156 Antisense
CGTTTTCTTTTCGATCTCTCAATCG 613 247 176 Antisense
CACCTGATTATCATTCCTATTTCAT 461 201 224 Antisense
Sequence Source Affymetrix Proprietary Database