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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0043086) negative regulation of catalytic activity [4, 0][dist]
                                 > (GO:0051352) negative regulation of ligase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051340) regulation of ligase activity [0,0]
                                 > (GO:0051352) negative regulation of ligase activity [0,0]
                                       -> (GO:0035228) negative regulation of glutamate-cysteine ligase activity [0,0]
                                       -> (GO:0051444) negative regulation of ubiquitin-protein ligase activity [0,0]