[Home] | [Total List]
   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002252) immune effector process [15, 0][dist]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0002381) immunoglobulin production during immune response [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002252) immune effector process [15, 0][dist]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002252) immune effector process [15, 0][dist]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002252) immune effector process [15, 0][dist]
                     > (GO:0002443) leukocyte mediated immunity [0,0]
                           > (GO:0002449) lymphocyte mediated immunity [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0042113) B cell activation [0,0]
                                 > (GO:0045190) isotype switching [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0042113) B cell activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0043170) macromolecule metabolic process [3980, 0][dist]
                     > (GO:0043283) biopolymer metabolic process [2693, 0][dist]
                           > (GO:0006259) DNA metabolic process [497, 33 ][dist]
                                 > (GO:0006310) DNA recombination [75, 64 ][dist]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0044237) cellular metabolic process [4703, 30 ][dist]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [1807, 18 ][dist]
                           > (GO:0006259) DNA metabolic process [497, 33 ][dist]
                                 > (GO:0006310) DNA recombination [75, 64 ][dist]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0044238) primary metabolic process [4742, 0][dist]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [1807, 18 ][dist]
                           > (GO:0006259) DNA metabolic process [497, 33 ][dist]
                                 > (GO:0006310) DNA recombination [75, 64 ][dist]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0042113) B cell activation [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0042113) B cell activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0051249) regulation of lymphocyte activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0050865) regulation of cell activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0044237) cellular metabolic process [4703, 30 ][dist]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [1807, 18 ][dist]
                           > (GO:0006259) DNA metabolic process [497, 33 ][dist]
                                 > (GO:0006310) DNA recombination [75, 64 ][dist]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032501) multicellular organismal process [4158, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032501) multicellular organismal process [4158, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032501) multicellular organismal process [4158, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032501) multicellular organismal process [4158, 0][dist]
               > (GO:0051239) regulation of multicellular organismal process [40, 0][dist]
                     > (GO:0050865) regulation of cell activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0007275) multicellular organismal development [3666, 62 ][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0048856) anatomical structure development [1369, 0][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0048856) anatomical structure development [1369, 0][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0032502) developmental process [3845, 0][dist]
               > (GO:0048856) anatomical structure development [1369, 0][dist]
                     > (GO:0048731) system development [850, 0][dist]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0045191) regulation of isotype switching [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0050789) regulation of biological process [2983, 0][dist]
                     > (GO:0051239) regulation of multicellular organismal process [40, 0][dist]
                           > (GO:0050865) regulation of cell activation [0,0]
                                 > (GO:0051249) regulation of lymphocyte activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   -> (GO:0045829) negative regulation of isotype switching [0,0]
                                                   -> (GO:0045830) positive regulation of isotype switching [0,0]
                                                   -> (GO:0048293) regulation of isotype switching to IgE isotypes [0,0]
                                                   -> (GO:0048296) regulation of isotype switching to IgA isotypes [0,0]
                                                   -> (GO:0048299) regulation of isotype switching to IgD isotypes [0,0]
                                                   -> (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]