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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0042221) response to chemical stimulus [275, 3 ][dist]
                     > (GO:0010033) response to organic substance [4, 0][dist]
                           > (GO:0043279) response to alkaloid [0,0]
                                 -> (GO:0031000) response to caffeine [0,0]
                                 -> (GO:0035094) response to nicotine [0,0]
                                 -> (GO:0042220) response to cocaine [0,0]
                                 -> (GO:0043278) response to morphine [0,0]