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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0007265) Ras protein signal transduction [96, 9 ][dist]
                                             > (GO:0032486) Rap protein signal transduction [0,0]
                                                   > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                                         > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0007265) Ras protein signal transduction [96, 9 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                         > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0007265) Ras protein signal transduction [96, 9 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                         > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0007265) Ras protein signal transduction [96, 9 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                                         > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                         > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                         > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007264) small GTPase mediated signal transduction [259, 155 ][dist]
                                       > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                             > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                                   > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                                         > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                               > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                   > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                   > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                                   > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0050794) regulation of cellular process [1228, 0][dist]
                     > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                           > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                 > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                       > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                             > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                   > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0050794) regulation of cellular process [1228, 0][dist]
                     > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                           > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                 > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                       > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                             > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                   > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0050794) regulation of cellular process [1228, 0][dist]
                     > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                           > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                 > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                       > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                             > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                   > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0050789) regulation of biological process [2983, 0][dist]
                     > (GO:0050794) regulation of cellular process [1228, 0][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                   > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0050789) regulation of biological process [2983, 0][dist]
                     > (GO:0050794) regulation of cellular process [1228, 0][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                                   > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0050789) regulation of biological process [2983, 0][dist]
                     > (GO:0050794) regulation of cellular process [1228, 0][dist]
                           > (GO:0009966) regulation of signal transduction [140, 1 ][dist]
                                 > (GO:0051056) regulation of small GTPase mediated signal transduction [103, 20 ][dist]
                                       > (GO:0046578) regulation of Ras protein signal transduction [85, 0][dist]
                                             > (GO:0032487) regulation of Rap protein signal transduction [0,0]
                                                   > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                         > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051336) regulation of hydrolase activity [33, 0][dist]
                                 > (GO:0043087) regulation of GTPase activity [33, 8 ][dist]
                                       > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                             > (GO:0032317) regulation of Rap GTPase activity [0,0]
                                                   > (GO:0032854) positive regulation of Rap GTPase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051336) regulation of hydrolase activity [33, 0][dist]
                                 > (GO:0043087) regulation of GTPase activity [33, 8 ][dist]
                                       > (GO:0032318) regulation of Ras GTPase activity [25, 0][dist]
                                             > (GO:0032320) positive regulation of Ras GTPase activity [0,0]
                                                   > (GO:0032854) positive regulation of Rap GTPase activity [0,0]
                                                         -> (GO:0032861) activation of Rap GTPase activity [0,0]