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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0019932) second-messenger-mediated signaling [28, 1 ][dist]
                                       > (GO:0019935) cyclic-nucleotide-mediated signaling [4, 0][dist]
                                             -> (GO:0007187) G-protein signaling, coupled to cyclic nucleotide second messenger [4, 0][dist]
                                             -> (GO:0019933) cAMP-mediated signaling [4, 0][dist]
                                             -> (GO:0019934) cGMP-mediated signaling [0,0]