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   > (GO:0003674) molecular_function [10671, 18 ][dist]
         > (GO:0003824) catalytic activity [4605, 555 ][dist]
               > (GO:0016787) hydrolase activity [2036, 274 ][dist]
                     > (GO:0016788) hydrolase activity, acting on ester bonds [662, 17 ][dist]
                           > (GO:0004518) nuclease activity [113, 19 ][dist]
                                 > (GO:0004519) endonuclease activity [48, 15 ][dist]
                                       > (GO:0016893) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [27, 0][dist]
                                             -> (GO:0016888) endodeoxyribonuclease activity, producing 5'-phosphomonoesters [13, 0][dist]
                                             -> (GO:0016891) endoribonuclease activity, producing 5'-phosphomonoesters [15, 3 ][dist]