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Cluster info 6grp_total_sub, cluster Increase

   > (GO:0003674) molecular_function [1678, 4 ] [dist]
         > (GO:0003824) catalytic activity [802, 63 ] [dist]
               > (GO:0016874) ligase activity [32, 10 ] [dist]
                     > (GO:0016879) ligase activity, forming carbon-nitrogen bonds [16, 1 ] [dist]
                           -> (GO:0003883) CTP synthase activity [0,0]
                           -> (GO:0003921) GMP synthase activity [0,0]
                           -> (GO:0004019) adenylosuccinate synthase activity [0,0]
                           -> (GO:0004055) argininosuccinate synthase activity [0,0]
                           -> (GO:0004075) biotin carboxylase activity [0,0]
                           -> (GO:0004086) carbamoyl-phosphate synthase activity [2, 2 ] [dist]
                           -> (GO:0004329) formate-tetrahydrofolate ligase activity [0,0]
                           -> (GO:0004637) phosphoribosylamine-glycine ligase activity [1, 1 ] [dist]
                           -> (GO:0004847) urea carboxylase activity [0,0]
                           -> (GO:0016880) acid-ammonia (or amide) ligase activity [4, 0] [dist]
                           -> (GO:0016881) acid-amino acid ligase activity [9, 0] [dist]
                           -> (GO:0016882) cyclo-ligase activity [1, 0] [dist]
                           -> (GO:0016884) carbon-nitrogen ligase activity, with glutamine as amido-N-donor [3, 0] [dist]
                           -> (GO:0016979) lipoate-protein ligase activity [0,0]
                           -> (GO:0018236) ribulose-bisphosphate carboxylase activase activity [0,0]
                           -> (GO:0018237) urease activase activity [0,0]
                           -> (GO:0018271) biotin-protein ligase activity [0,0]
                           -> (GO:0019776) Atg8 ligase activity [0,0]
                           -> (GO:0032267) tRNA(Ile)-lysidine synthase [0,0]

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