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   > (GO:0003674) molecular_function [10671, 18 ][dist]
         > (GO:0003824) catalytic activity [4605, 555 ][dist]
               > (GO:0016829) lyase activity [184, 20 ][dist]
                     > (GO:0016835) carbon-oxygen lyase activity [51, 0][dist]
                           > (GO:0016836) hydro-lyase activity [48, 2 ][dist]
                                 -> (GO:0003855) 3-dehydroquinate dehydratase activity [0,0]
                                 -> (GO:0003859) 3-hydroxybutyryl-CoA dehydratase activity [0,0]
                                 -> (GO:0003861) 3-isopropylmalate dehydratase activity [1, 1 ][dist]
                                 -> (GO:0003994) aconitate hydratase activity [1, 1 ][dist]
                                 -> (GO:0004089) carbonate dehydratase activity [11, 11 ][dist]
                                 -> (GO:0004122) cystathionine beta-synthase activity [10, 10 ][dist]
                                 -> (GO:0004160) dihydroxy-acid dehydratase activity [0,0]
                                 -> (GO:0004300) enoyl-CoA hydratase activity [8, 8 ][dist]
                                 -> (GO:0004333) fumarate hydratase activity [0,0]
                                 -> (GO:0004409) homoaconitate hydratase activity [1, 1 ][dist]
                                 -> (GO:0004424) imidazoleglycerol-phosphate dehydratase activity [0,0]
                                 -> (GO:0004456) phosphogluconate dehydratase activity [0,0]
                                 -> (GO:0004490) methylglutaconyl-CoA hydratase activity [0,0]
                                 -> (GO:0004634) phosphopyruvate hydratase activity [2, 2 ][dist]
                                 -> (GO:0004655) porphobilinogen synthase activity [0,0]
                                 -> (GO:0004664) prephenate dehydratase activity [0,0]
                                 -> (GO:0004730) pseudouridylate synthase activity [6, 6 ][dist]
                                 -> (GO:0004834) tryptophan synthase activity [7, 7 ][dist]
                                 -> (GO:0004852) uroporphyrinogen-III synthase activity [0,0]
                                 -> (GO:0008124) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [0,0]
                                 -> (GO:0008446) GDP-mannose 4,6-dehydratase activity [6, 6 ][dist]
                                 -> (GO:0008460) dTDP-glucose 4,6-dehydratase activity [7, 7 ][dist]
                                 -> (GO:0008659) (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity [0,0]
                                 -> (GO:0008684) 2-oxopent-4-enoate hydratase activity [0,0]
                                 -> (GO:0008730) L(+)-tartrate dehydratase activity [0,0]
                                 -> (GO:0008735) carnitine dehydratase activity [0,0]
                                 -> (GO:0008789) altronate dehydratase activity [0,0]
                                 -> (GO:0008840) dihydrodipicolinate synthase activity [0,0]
                                 -> (GO:0008867) galactarate dehydratase activity [0,0]
                                 -> (GO:0008869) galactonate dehydratase activity [0,0]
                                 -> (GO:0008872) glucarate dehydratase activity [0,0]
                                 -> (GO:0008927) mannonate dehydratase activity [0,0]
                                 -> (GO:0009978) allene oxide synthase activity [0,0]
                                 -> (GO:0016153) urocanate hydratase activity [1, 1 ][dist]
                                 -> (GO:0016508) long-chain-enoyl-CoA hydratase activity [0,0]
                                 -> (GO:0017051) retinol dehydratase activity [0,0]
                                 -> (GO:0018128) peptidyl-serine cyclase activity [0,0]
                                 -> (GO:0018135) peptidyl-cysteine cyclase activity [0,0]
                                 -> (GO:0018807) 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity [0,0]
                                 -> (GO:0018808) cis-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity [0,0]
                                 -> (GO:0018809) E-phenylitaconyl-CoA hydratase activity [0,0]
                                 -> (GO:0018810) trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity [0,0]
                                 -> (GO:0018811) cyclohex-1-ene-1-carboxyl-CoA hydratase activity [0,0]
                                 -> (GO:0018812) 3-hydroxyacyl-CoA dehydratase activity [0,0]
                                 -> (GO:0018813) trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity [0,0]
                                 -> (GO:0018815) 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity [0,0]
                                 -> (GO:0018816) 2-hydroxyisobutyrate dehydratase activity [0,0]
                                 -> (GO:0018817) 2-oxo-hept-3-ene-1,7-dioate hydratase activity [0,0]
                                 -> (GO:0018818) acetylene hydratase activity [0,0]
                                 -> (GO:0018819) lactoyl-CoA dehydratase activity [0,0]
                                 -> (GO:0018820) cyanamide hydratase activity [0,0]
                                 -> (GO:0018822) nitrile hydratase activity [0,0]
                                 -> (GO:0018823) cyclohexa-1,5-dienecarbonyl-CoA hydratase activity [0,0]
                                 -> (GO:0019171) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [0,0]
                                 -> (GO:0030196) cyanide hydratase activity [0,0]
                                 -> (GO:0030411) scytalone dehydratase activity [0,0]
                                 -> (GO:0033987) 2-hydroxyisoflavanone dehydratase activity [0,0]
                                 -> (GO:0033988) bile-acid 7alpha-dehydratase activity [0,0]
                                 -> (GO:0033989) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity [0,0]
                                 -> (GO:0033990) ectoine synthase activity [0,0]
                                 -> (GO:0033991) aldos-2-ulose dehydratase activity [0,0]
                                 -> (GO:0033992) 1,5-anhydro-D-fructose dehydratase activity [0,0]
                                 -> (GO:0034561) 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity [0,0]
                                 -> (GO:0034578) limonene 8-hydratase activity [0,0]
                                 -> (GO:0034581) 4-methyloct-2-enoyl-CoA hydratase activity [0,0]
                                 -> (GO:0034829) 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity [0,0]
                                 -> (GO:0034839) menth-2-enone hydratase activity [0,0]
                                 -> (GO:0034846) naphthyl-2-methylene-succinyl-CoA lyase activity [0,0]
                                 -> (GO:0034856) 2-hydroxyhexa-2,4-dienoate hydratase activity [0,0]
                                 -> (GO:0034867) 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity [0,0]
                                 -> (GO:0034890) endosulfan diol hydrolyase (cyclizing) activity [0,0]
                                 -> (GO:0034904) 5-chloro-2-oxopent-4-enoate hydratase activity [0,0]
                                 -> (GO:0034917) 2-methylhex-2-enoyl-CoA hydratase activity [0,0]
                                 -> (GO:0034953) perillyl-CoA hydratase activity [0,0]
                                 -> (GO:0043717) 2-hydroxyglutaryl-CoA dehydratase activity [0,0]
                                 -> (GO:0043721) 4-hydroxybutyryl-CoA dehydratase activity [0,0]
                                 -> (GO:0043724) 2-keto-3-deoxygalactonate aldolase activity [0,0]
                                 -> (GO:0043725) 2-keto-3-deoxygluconate aldolase activity [0,0]
                                 -> (GO:0043748) O-succinylbenzoate synthase activity [0,0]
                                 -> (GO:0043809) methylthioribulose 1-phosphate dehydratase activity [0,0]
                                 -> (GO:0043881) mesaconyl-CoA hydratase activity [0,0]
                                 -> (GO:0043956) 3-hydroxypropionyl-CoA dehydratase activity [0,0]
                                 -> (GO:0043960) L-erythro-3-methylmalyl-CoA dehydratase activity [0,0]
                                 -> (GO:0046405) glycerol dehydratase activity [0,0]
                                 -> (GO:0046565) 3-dehydroshikimate dehydratase activity [0,0]
                                 -> (GO:0046570) 5-methylthioribulose-1-phosphate 4-dehydratase activity [0,0]
                                 -> (GO:0047448) 5-dehydro-4-deoxyglucarate dehydratase activity [0,0]
                                 -> (GO:0047449) 2-dehydro-3-deoxy-L-arabinonate dehydratase activity [0,0]
                                 -> (GO:0047450) crotonoyl-[acyl-carrier-protein] hydratase activity [0,0]
                                 -> (GO:0047452) protoaphin-aglucone dehydratase (cyclizing) activity [0,0]
                                 -> (GO:0047453) ATP-dependent NAD(P)H-hydrate dehydratase activity [0,0]
                                 -> (GO:0047454) phaseollidin hydratase activity [0,0]
                                 -> (GO:0047455) 16-alpha-hydroxyprogesterone dehydratase activity [0,0]
                                 -> (GO:0047456) 2-methylisocitrate dehydratase activity [0,0]
                                 -> (GO:0047508) (R)-2-methylmalate dehydratase activity [0,0]
                                 -> (GO:0047510) (S)-2-methylmalate dehydratase activity [0,0]
                                 -> (GO:0047547) 2-methylcitrate dehydratase activity [0,0]
                                 -> (GO:0047558) 3-cyanoalanine hydratase activity [0,0]
                                 -> (GO:0047584) 4-oxalmesaconate hydratase activity [0,0]
                                 -> (GO:0047587) 5-alpha-hydroxysteroid dehydratase activity [0,0]
                                 -> (GO:0047675) arabinonate dehydratase activity [0,0]
                                 -> (GO:0047733) CDP-glucose 4,6-dehydratase activity [0,0]
                                 -> (GO:0047769) arogenate dehydratase activity [0,0]
                                 -> (GO:0047780) citrate dehydratase activity [0,0]
                                 -> (GO:0047808) D(-)-tartrate dehydratase activity [0,0]
                                 -> (GO:0047818) D-fuconate dehydratase activity [0,0]
                                 -> (GO:0047820) D-glutamate cyclase activity [0,0]
                                 -> (GO:0047868) dimethylmaleate hydratase activity [0,0]
                                 -> (GO:0047929) gluconate dehydratase activity [0,0]
                                 -> (GO:0047987) hydroperoxide dehydratase activity [0,0]
                                 -> (GO:0050005) isohexenylglutaconyl-CoA hydratase activity [0,0]
                                 -> (GO:0050011) itaconyl-CoA hydratase activity [0,0]
                                 -> (GO:0050015) kievitone hydratase activity [0,0]
                                 -> (GO:0050020) L-arabinonate dehydratase activity [0,0]
                                 -> (GO:0050023) L-fuconate dehydratase activity [0,0]
                                 -> (GO:0050032) L-rhamnonate dehydratase activity [0,0]
                                 -> (GO:0050075) maleate hydratase activity [0,0]
                                 -> (GO:0050079) acetylenecarboxylate hydratase activity, producing 3-oxopropanoate [0,0]
                                 -> (GO:0050114) myo-inosose-2 dehydratase activity [0,0]
                                 -> (GO:0050151) oleate hydratase activity [0,0]
                                 -> (GO:0050202) octopamine dehydratase activity [0,0]
                                 -> (GO:0050215) propanediol dehydratase activity [0,0]
                                 -> (GO:0050234) pyrazolylalanine synthase activity [0,0]
                                 -> (GO:0050315) synephrine dehydratase activity [0,0]
                                 -> (GO:0050346) trans-L-3-hydroxyproline dehydratase activity [0,0]
                                 -> (GO:0050377) UDP-glucose 4,6-dehydratase activity [0,0]
                                 -> (GO:0050401) xylonate dehydratase activity [0,0]
                                 -> (GO:0050474) (S)-norcoclaurine synthase activity [0,0]
                                 -> (GO:0050548) trans-feruloyl-CoA hydratase activity [0,0]
                                 -> (GO:0050549) cyclohexyl-isocyanide hydratase activity [0,0]
                                 -> (GO:0051909) acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate [0,0]
                                 -> (GO:0080023) 3R-hydroxyacyl-CoA dehydratase activity [0,0]