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   > (GO:0003674) molecular_function [10671, 18 ][dist]
         > (GO:0003824) catalytic activity [4605, 555 ][dist]
               > (GO:0008641) small protein activating enzyme activity [4, 3 ][dist]
                     -> (GO:0004839) ubiquitin activating enzyme activity [2, 2 ][dist]
                     -> (GO:0019778) APG12 activating enzyme activity [0,0]
                     -> (GO:0019779) APG8 activating enzyme activity [0,0]
                     -> (GO:0019780) FAT10 activating enzyme activity [0,0]
                     -> (GO:0019781) NEDD8 activating enzyme activity [0,0]
                     -> (GO:0019782) ISG15 activating enzyme activity [0,0]
                     -> (GO:0019948) SUMO activating enzyme activity [0,0]
                     -> (GO:0042292) URM1 activating enzyme activity [0,0]
                     -> (GO:0042293) Hub1 activating enzyme activity [0,0]