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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007166) cell surface receptor linked signal transduction [636, 10 ][dist]
                                 > (GO:0007167) enzyme linked receptor protein signaling pathway [67, 0][dist]
                                       > (GO:0007169) transmembrane receptor protein tyrosine kinase signaling pathway [43, 4 ][dist]
                                             > (GO:0008286) insulin receptor signaling pathway [14, 10 ][dist]
                                                   -> (GO:0046626) regulation of insulin receptor signaling pathway [4, 4 ][dist]
                                                   -> (GO:0046627) negative regulation of insulin receptor signaling pathway [0,0]
                                                   -> (GO:0046628) positive regulation of insulin receptor signaling pathway [0,0]