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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007243) protein kinase cascade [18, 3 ][dist]
                                       > (GO:0007259) JAK-STAT cascade [0,0]
                                             -> (GO:0007260) tyrosine phosphorylation of STAT protein [0,0]
                                             -> (GO:0007261) JAK-induced STAT protein dimerization [0,0]
                                             -> (GO:0007262) STAT protein nuclear translocation [0,0]
                                             -> (GO:0042501) serine phosphorylation of STAT protein [0,0]
                                             -> (GO:0042976) activation of Janus kinase activity [0,0]
                                             -> (GO:0046425) regulation of JAK-STAT cascade [0,0]
                                             -> (GO:0046426) negative regulation of JAK-STAT cascade [0,0]
                                             -> (GO:0046427) positive regulation of JAK-STAT cascade [0,0]
                                             -> (GO:0060397) JAK-STAT cascade involved in growth hormone signaling pathway [0,0]