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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007243) protein kinase cascade [18, 3 ][dist]
                                       -> (GO:0000165) MAPKKK cascade [15, 3 ][dist]
                                       -> (GO:0007249) I-kappaB kinase/NF-kappaB cascade [0,0]
                                       -> (GO:0007259) JAK-STAT cascade [0,0]
                                       -> (GO:0010627) regulation of protein kinase cascade [0,0]
                                       -> (GO:0010737) protein kinase A signaling cascade [0,0]
                                       -> (GO:0010740) positive regulation of protein kinase cascade [0,0]
                                       -> (GO:0010741) negative regulation of protein kinase cascade [0,0]
                                       -> (GO:0014065) phosphoinositide 3-kinase cascade [0,0]
                                       -> (GO:0043491) protein kinase B signaling cascade [0,0]
                                       -> (GO:0070528) protein kinase C signaling cascade [0,0]