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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007166) cell surface receptor linked signal transduction [636, 10 ][dist]
                                 > (GO:0007186) G-protein coupled receptor protein signaling pathway [525, 475 ][dist]
                                       > (GO:0007187) G-protein signaling, coupled to cyclic nucleotide second messenger [4, 0][dist]
                                             > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                   > (GO:0007189) activation of adenylate cyclase activity by G-protein signaling pathway [2, 0][dist]
                                                         > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007166) cell surface receptor linked signal transduction [636, 10 ][dist]
                                 > (GO:0007186) G-protein coupled receptor protein signaling pathway [525, 475 ][dist]
                                       > (GO:0007187) G-protein signaling, coupled to cyclic nucleotide second messenger [4, 0][dist]
                                             > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                   > (GO:0045761) regulation of adenylate cyclase activity [0,0]
                                                         > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                                               > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0019932) second-messenger-mediated signaling [28, 1 ][dist]
                                       > (GO:0019935) cyclic-nucleotide-mediated signaling [4, 0][dist]
                                             > (GO:0007187) G-protein signaling, coupled to cyclic nucleotide second messenger [4, 0][dist]
                                                   > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                         > (GO:0007189) activation of adenylate cyclase activity by G-protein signaling pathway [2, 0][dist]
                                                               > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0019932) second-messenger-mediated signaling [28, 1 ][dist]
                                       > (GO:0019935) cyclic-nucleotide-mediated signaling [4, 0][dist]
                                             > (GO:0007187) G-protein signaling, coupled to cyclic nucleotide second messenger [4, 0][dist]
                                                   > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                         > (GO:0045761) regulation of adenylate cyclase activity [0,0]
                                                               > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                                                     > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0019932) second-messenger-mediated signaling [28, 1 ][dist]
                                       > (GO:0019935) cyclic-nucleotide-mediated signaling [4, 0][dist]
                                             > (GO:0019933) cAMP-mediated signaling [4, 0][dist]
                                                   > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                         > (GO:0007189) activation of adenylate cyclase activity by G-protein signaling pathway [2, 0][dist]
                                                               > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0019932) second-messenger-mediated signaling [28, 1 ][dist]
                                       > (GO:0019935) cyclic-nucleotide-mediated signaling [4, 0][dist]
                                             > (GO:0019933) cAMP-mediated signaling [4, 0][dist]
                                                   > (GO:0007188) G-protein signaling, coupled to cAMP nucleotide second messenger [4, 2 ][dist]
                                                         > (GO:0045761) regulation of adenylate cyclase activity [0,0]
                                                               > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                                                     > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0031279) regulation of cyclase activity [0,0]
                                 > (GO:0031281) positive regulation of cyclase activity [0,0]
                                       > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                             > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0031279) regulation of cyclase activity [0,0]
                                 > (GO:0045761) regulation of adenylate cyclase activity [0,0]
                                       > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                             > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0043085) positive regulation of catalytic activity [25, 1 ][dist]
                                 > (GO:0051349) positive regulation of lyase activity [0,0]
                                       > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                             > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051339) regulation of lyase activity [0,0]
                                 > (GO:0045761) regulation of adenylate cyclase activity [0,0]
                                       > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                             > (GO:0007190) activation of adenylate cyclase activity [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051339) regulation of lyase activity [0,0]
                                 > (GO:0051349) positive regulation of lyase activity [0,0]
                                       > (GO:0045762) positive regulation of adenylate cyclase activity [0,0]
                                             > (GO:0007190) activation of adenylate cyclase activity [0,0]
                                                   -> (GO:0007189) activation of adenylate cyclase activity by G-protein signaling pathway [2, 0][dist]