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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0006984) ER-nuclear signaling pathway [10, 0][dist]
                                       > (GO:0030968) endoplasmic reticulum unfolded protein response [10, 8 ][dist]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006950) response to stress [586, 31 ][dist]
                     > (GO:0006986) response to unfolded protein [10, 0][dist]
                           > (GO:0030968) endoplasmic reticulum unfolded protein response [10, 8 ][dist]
                                 > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0009607) response to biotic stimulus [17, 1 ][dist]
                     > (GO:0006986) response to unfolded protein [10, 0][dist]
                           > (GO:0030968) endoplasmic reticulum unfolded protein response [10, 8 ][dist]
                                 > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0042221) response to chemical stimulus [275, 3 ][dist]
                     > (GO:0051789) response to protein stimulus [10, 0][dist]
                           > (GO:0006986) response to unfolded protein [10, 0][dist]
                                 > (GO:0030968) endoplasmic reticulum unfolded protein response [10, 8 ][dist]
                                       > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0043085) positive regulation of catalytic activity [25, 1 ][dist]
                                 > (GO:0051345) positive regulation of hydrolase activity [0,0]
                                       > (GO:0032075) positive regulation of nuclease activity [0,0]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0043085) positive regulation of catalytic activity [25, 1 ][dist]
                                 > (GO:0051347) positive regulation of transferase activity [24, 0][dist]
                                       > (GO:0045860) positive regulation of protein kinase activity [24, 1 ][dist]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051336) regulation of hydrolase activity [33, 0][dist]
                                 > (GO:0032069) regulation of nuclease activity [0,0]
                                       > (GO:0032075) positive regulation of nuclease activity [0,0]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051336) regulation of hydrolase activity [33, 0][dist]
                                 > (GO:0051345) positive regulation of hydrolase activity [0,0]
                                       > (GO:0032075) positive regulation of nuclease activity [0,0]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051338) regulation of transferase activity [30, 0][dist]
                                 > (GO:0043549) regulation of kinase activity [30, 0][dist]
                                       > (GO:0045859) regulation of protein kinase activity [30, 0][dist]
                                             > (GO:0045860) positive regulation of protein kinase activity [24, 1 ][dist]
                                                   > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0065007) biological regulation [3158, 0][dist]
               > (GO:0065009) regulation of molecular function [67, 0][dist]
                     > (GO:0050790) regulation of catalytic activity [64, 0][dist]
                           > (GO:0051338) regulation of transferase activity [30, 0][dist]
                                 > (GO:0051347) positive regulation of transferase activity [24, 0][dist]
                                       > (GO:0045860) positive regulation of protein kinase activity [24, 1 ][dist]
                                             > (GO:0006987) activation of signaling protein activity involved in unfolded protein response [0,0]