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Cluster info 6grp_highest_sub, cluster Da

   > (GO:0003674) molecular_function [421, 0] [dist]
         > (GO:0003824) catalytic activity [202, 25 ] [dist]
               > (GO:0016853) isomerase activity [4, 0] [dist]
                     > (GO:0003916) DNA topoisomerase activity [2, 0] [dist]

   > (GO:0003674) molecular_function [421, 0] [dist]
         > (GO:0005488) binding [292, 33 ] [dist]
               > (GO:0003676) nucleic acid binding [131, 65 ] [dist]
                     > (GO:0003677) DNA binding [63, 52 ] [dist]
                           > (GO:0003916) DNA topoisomerase activity [2, 0] [dist]
                                 -> (GO:0003917) DNA topoisomerase type I activity [0,0]
                                 -> (GO:0003918) DNA topoisomerase (ATP-hydrolyzing) activity [2, 2 ] [dist]