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Cluster info 6grp_highest_sub, cluster De

   > (GO:0003674) molecular_function [1103, 0] [dist]
         > (GO:0003824) catalytic activity [416, 53 ] [dist]
               > (GO:0016853) isomerase activity [7, 2 ] [dist]
                     > (GO:0003916) DNA topoisomerase activity [1, 0] [dist]

   > (GO:0003674) molecular_function [1103, 0] [dist]
         > (GO:0005488) binding [646, 61 ] [dist]
               > (GO:0003676) nucleic acid binding [177, 60 ] [dist]
                     > (GO:0003677) DNA binding [118, 97 ] [dist]
                           > (GO:0003916) DNA topoisomerase activity [1, 0] [dist]
                                 -> (GO:0003917) DNA topoisomerase type I activity [1, 1 ] [dist]
                                 -> (GO:0003918) DNA topoisomerase (ATP-hydrolyzing) activity [0,0]