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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0002252) immune effector process [15, 0][dist]
                     > (GO:0002443) leukocyte mediated immunity [0,0]
                           > (GO:0002449) lymphocyte mediated immunity [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0002376) immune system process [27, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0006959) humoral immune response [15, 0][dist]
                           > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0002252) immune effector process [15, 0][dist]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0050896) response to stimulus [2137, 0][dist]
               > (GO:0006955) immune response [27, 7 ][dist]
                     > (GO:0006959) humoral immune response [15, 0][dist]
                           > (GO:0002455) humoral immune response mediated by circulating immunoglobulin [0,0]
                                 -> (GO:0002923) regulation of humoral immune response mediated by circulating immunoglobulin [0,0]
                                 -> (GO:0002924) negative regulation of humoral immune response mediated by circulating immunoglobulin [0,0]
                                 -> (GO:0002925) positive regulation of humoral immune response mediated by circulating immunoglobulin [0,0]
                                 -> (GO:0006958) complement activation, classical pathway [0,0]