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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0007154) cell communication [1545, 59 ][dist]
                     > (GO:0007165) signal transduction [1432, 444 ][dist]
                           > (GO:0007242) intracellular signaling cascade [580, 279 ][dist]
                                 > (GO:0007243) protein kinase cascade [18, 3 ][dist]
                                       > (GO:0000165) MAPKKK cascade [15, 3 ][dist]
                                             -> (GO:0000161) MAPKKK cascade during osmolarity sensing [0,0]
                                             -> (GO:0000196) MAPKKK cascade during cell wall biogenesis [0,0]
                                             -> (GO:0007254) JNK cascade [9, 0][dist]
                                             -> (GO:0051403) stress-activated MAPK cascade [0,0]
                                             -> (GO:0070371) ERK1 and ERK2 cascade [0,0]
                                             -> (GO:0070375) BMK cascade [0,0]
                                             -> (GO:0000185) activation of MAPKKK activity [0,0]
                                             -> (GO:0000186) activation of MAPKK activity [2, 2 ][dist]
                                             -> (GO:0000187) activation of MAPK activity [5, 3 ][dist]
                                             -> (GO:0000188) inactivation of MAPK activity [2, 2 ][dist]
                                             -> (GO:0000189) nuclear translocation of MAPK [0,0]
                                             -> (GO:0043408) regulation of MAPKKK cascade [2, 0][dist]
                                             -> (GO:0043409) negative regulation of MAPKKK cascade [2, 2 ][dist]
                                             -> (GO:0043410) positive regulation of MAPKKK cascade [0,0]
                                             -> (GO:0051389) inactivation of MAPKK activity [0,0]
                                             -> (GO:0051390) inactivation of MAPKKK activity [0,0]