Total Probe ID GeneTitle GeneSymbol Gene Ontology GeneBank ID 4i6i 4i6d 4d6i 4d6d

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    Dauer Comparison : 4d6d

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002200) somatic diversification of immune receptors [0,0]
                     > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                           > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                 > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0002381) immunoglobulin production during immune response [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0002381) immunoglobulin production during immune response [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0045191) regulation of isotype switching [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002440) production of molecular mediator of immune response [0,0]
                           > (GO:0002377) immunoglobulin production [0,0]
                                 > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                       > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                             > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                   > (GO:0045190) isotype switching [0,0]
                                                         > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                               > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002443) leukocyte mediated immunity [0,0]
                           > (GO:0002449) lymphocyte mediated immunity [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002252) immune effector process [0,0]
                     > (GO:0002443) leukocyte mediated immunity [0,0]
                           > (GO:0002449) lymphocyte mediated immunity [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0045191) regulation of isotype switching [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0002520) immune system development [0,0]
                     > (GO:0002200) somatic diversification of immune receptors [0,0]
                           > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                 > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                       > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                             > (GO:0045190) isotype switching [0,0]
                                                   > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                         > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0045191) regulation of isotype switching [0,0]
                                                                                 > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                                 > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0042113) B cell activation [0,0]
                                 > (GO:0045190) isotype switching [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0042113) B cell activation [0,0]
                                 > (GO:0045190) isotype switching [0,0]
                                       > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0042113) B cell activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0002376) immune system process [0,0]
               > (GO:0045321) leukocyte activation [0,0]
                     > (GO:0046649) lymphocyte activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0043170) macromolecule metabolic process [133, 0]
                     > (GO:0043283) biopolymer metabolic process [4, 0]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0043170) macromolecule metabolic process [133, 0]
                     > (GO:0043283) biopolymer metabolic process [4, 0]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0044237) cellular metabolic process [53, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0044237) cellular metabolic process [53, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0044238) primary metabolic process [13, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0008152) metabolic process [322, 52 ]
               > (GO:0044238) primary metabolic process [13, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0042113) B cell activation [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0042113) B cell activation [0,0]
                                       > (GO:0045190) isotype switching [0,0]
                                             > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0042113) B cell activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0045321) leukocyte activation [0,0]
                           > (GO:0046649) lymphocyte activation [0,0]
                                 > (GO:0051249) regulation of lymphocyte activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0001775) cell activation [0,0]
                     > (GO:0050865) regulation of cell activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0044237) cellular metabolic process [53, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0009987) cellular process [83, 0]
               > (GO:0044237) cellular metabolic process [53, 0]
                     > (GO:0006139) nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [6, 1 ]
                           > (GO:0006259) DNA metabolic process [2, 0]
                                 > (GO:0006310) DNA recombination [0,0]
                                       > (GO:0016444) somatic cell DNA recombination [0,0]
                                             > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                                   > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032501) multicellular organismal process [0,0]
               > (GO:0051239) regulation of multicellular organismal process [2, 0]
                     > (GO:0050865) regulation of cell activation [0,0]
                           > (GO:0051249) regulation of lymphocyte activation [0,0]
                                 > (GO:0050864) regulation of B cell activation [0,0]
                                       > (GO:0045191) regulation of isotype switching [0,0]
                                             > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0007275) multicellular organismal development [59, 5 ]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0002562) somatic diversification of immune receptors via germline recombination within a single locus [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0032502) developmental process [0,0]
               > (GO:0048856) anatomical structure development [0,0]
                     > (GO:0048731) system development [4, 0]
                           > (GO:0002520) immune system development [0,0]
                                 > (GO:0002200) somatic diversification of immune receptors [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0045191) regulation of isotype switching [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002250) adaptive immune response [0,0]
                           > (GO:0002460) adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [0,0]
                                 > (GO:0019724) B cell mediated immunity [0,0]
                                       > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                             > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                   > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                         > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                               > (GO:0045190) isotype switching [0,0]
                                                                     > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                           > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0002381) immunoglobulin production during immune response [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0045191) regulation of isotype switching [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002440) production of molecular mediator of immune response [0,0]
                                 > (GO:0002377) immunoglobulin production [0,0]
                                       > (GO:0016445) somatic diversification of immunoglobulins [0,0]
                                             > (GO:0016447) somatic recombination of immunoglobulin gene segments [0,0]
                                                   > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                         > (GO:0045190) isotype switching [0,0]
                                                               > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                     > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0045191) regulation of isotype switching [0,0]
                                                                                 > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0050896) response to stimulus [19, 0]
               > (GO:0006955) immune response [2, 1 ]
                     > (GO:0002252) immune effector process [0,0]
                           > (GO:0002443) leukocyte mediated immunity [0,0]
                                 > (GO:0002449) lymphocyte mediated immunity [0,0]
                                       > (GO:0019724) B cell mediated immunity [0,0]
                                             > (GO:0016064) immunoglobulin mediated immune response [0,0]
                                                   > (GO:0002381) immunoglobulin production during immune response [0,0]
                                                         > (GO:0002208) somatic diversification of immunoglobulins during immune response [0,0]
                                                               > (GO:0002204) somatic recombination of immunoglobulin genes during immune response [0,0]
                                                                     > (GO:0045190) isotype switching [0,0]
                                                                           > (GO:0048291) isotype switching to IgG isotypes [0,0]
                                                                                 > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]

   > (GO:0008150) biological_process [543, 0]
         > (GO:0065007) biological regulation [0,0]
               > (GO:0050789) regulation of biological process [0,0]
                     > (GO:0051239) regulation of multicellular organismal process [2, 0]
                           > (GO:0050865) regulation of cell activation [0,0]
                                 > (GO:0051249) regulation of lymphocyte activation [0,0]
                                       > (GO:0050864) regulation of B cell activation [0,0]
                                             > (GO:0045191) regulation of isotype switching [0,0]
                                                   > (GO:0048302) regulation of isotype switching to IgG isotypes [0,0]
                                                         -> (GO:0048303) negative regulation of isotype switching to IgG isotypes [0,0]
                                                         -> (GO:0048304) positive regulation of isotype switching to IgG isotypes [0,0]