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   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0000003) reproduction [2098, 1104 ][dist]
               > (GO:0019953) sexual reproduction [821, 0][dist]
                     > (GO:0009566) fertilization [62, 0][dist]
                           > (GO:0007338) single fertilization [62, 1 ][dist]
                                 > (GO:0007340) acrosome reaction [0,0]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0000003) reproduction [2098, 1104 ][dist]
               > (GO:0022414) reproductive process [1010, 0][dist]
                     > (GO:0009566) fertilization [62, 0][dist]
                           > (GO:0007338) single fertilization [62, 1 ][dist]
                                 > (GO:0007340) acrosome reaction [0,0]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0043170) macromolecule metabolic process [3980, 0][dist]
                     > (GO:0019538) protein metabolic process [2296, 13 ][dist]
                           > (GO:0044267) cellular protein metabolic process [2210, 11 ][dist]
                                 > (GO:0006508) proteolysis [594, 525 ][dist]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0043170) macromolecule metabolic process [3980, 0][dist]
                     > (GO:0044260) cellular macromolecule metabolic process [2289, 0][dist]
                           > (GO:0044267) cellular protein metabolic process [2210, 11 ][dist]
                                 > (GO:0006508) proteolysis [594, 525 ][dist]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0044237) cellular metabolic process [4703, 30 ][dist]
                     > (GO:0044260) cellular macromolecule metabolic process [2289, 0][dist]
                           > (GO:0044267) cellular protein metabolic process [2210, 11 ][dist]
                                 > (GO:0006508) proteolysis [594, 525 ][dist]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0008152) metabolic process [5617, 690 ][dist]
               > (GO:0044238) primary metabolic process [4742, 0][dist]
                     > (GO:0019538) protein metabolic process [2296, 13 ][dist]
                           > (GO:0044267) cellular protein metabolic process [2210, 11 ][dist]
                                 > (GO:0006508) proteolysis [594, 525 ][dist]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0016043) cellular component organization and biogenesis [1214, 8 ][dist]
                     > (GO:0051641) cellular localization [488, 0][dist]
                           > (GO:0051649) establishment of cellular localization [477, 0][dist]
                                 > (GO:0032940) secretion by cell [97, 0][dist]
                                       > (GO:0045045) secretory pathway [61, 2 ][dist]
                                             > (GO:0006887) exocytosis [21, 3 ][dist]
                                                   > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                                         > (GO:0007340) acrosome reaction [0,0]
                                                               > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0009987) cellular process [6692, 0][dist]
               > (GO:0044237) cellular metabolic process [4703, 30 ][dist]
                     > (GO:0044260) cellular macromolecule metabolic process [2289, 0][dist]
                           > (GO:0044267) cellular protein metabolic process [2210, 11 ][dist]
                                 > (GO:0006508) proteolysis [594, 525 ][dist]
                                       > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0022414) reproductive process [1010, 0][dist]
               > (GO:0009566) fertilization [62, 0][dist]
                     > (GO:0007338) single fertilization [62, 1 ][dist]
                           > (GO:0007340) acrosome reaction [0,0]
                                 > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051179) localization [2100, 8 ][dist]
               > (GO:0051234) establishment of localization [1959, 0][dist]
                     > (GO:0006810) transport [1844, 607 ][dist]
                           > (GO:0016192) vesicle-mediated transport [145, 53 ][dist]
                                 > (GO:0006887) exocytosis [21, 3 ][dist]
                                       > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                             > (GO:0007340) acrosome reaction [0,0]
                                                   > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051179) localization [2100, 8 ][dist]
               > (GO:0051234) establishment of localization [1959, 0][dist]
                     > (GO:0006810) transport [1844, 607 ][dist]
                           > (GO:0045045) secretory pathway [61, 2 ][dist]
                                 > (GO:0006887) exocytosis [21, 3 ][dist]
                                       > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                             > (GO:0007340) acrosome reaction [0,0]
                                                   > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051179) localization [2100, 8 ][dist]
               > (GO:0051234) establishment of localization [1959, 0][dist]
                     > (GO:0046903) secretion [97, 0][dist]
                           > (GO:0032940) secretion by cell [97, 0][dist]
                                 > (GO:0045045) secretory pathway [61, 2 ][dist]
                                       > (GO:0006887) exocytosis [21, 3 ][dist]
                                             > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                                   > (GO:0007340) acrosome reaction [0,0]
                                                         > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051179) localization [2100, 8 ][dist]
               > (GO:0051234) establishment of localization [1959, 0][dist]
                     > (GO:0051649) establishment of cellular localization [477, 0][dist]
                           > (GO:0032940) secretion by cell [97, 0][dist]
                                 > (GO:0045045) secretory pathway [61, 2 ][dist]
                                       > (GO:0006887) exocytosis [21, 3 ][dist]
                                             > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                                   > (GO:0007340) acrosome reaction [0,0]
                                                         > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051179) localization [2100, 8 ][dist]
               > (GO:0051641) cellular localization [488, 0][dist]
                     > (GO:0051649) establishment of cellular localization [477, 0][dist]
                           > (GO:0032940) secretion by cell [97, 0][dist]
                                 > (GO:0045045) secretory pathway [61, 2 ][dist]
                                       > (GO:0006887) exocytosis [21, 3 ][dist]
                                             > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                                   > (GO:0007340) acrosome reaction [0,0]
                                                         > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051234) establishment of localization [1959, 0][dist]
               > (GO:0006810) transport [1844, 607 ][dist]
                     > (GO:0016192) vesicle-mediated transport [145, 53 ][dist]
                           > (GO:0006887) exocytosis [21, 3 ][dist]
                                 > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                       > (GO:0007340) acrosome reaction [0,0]
                                             > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051234) establishment of localization [1959, 0][dist]
               > (GO:0006810) transport [1844, 607 ][dist]
                     > (GO:0045045) secretory pathway [61, 2 ][dist]
                           > (GO:0006887) exocytosis [21, 3 ][dist]
                                 > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                       > (GO:0007340) acrosome reaction [0,0]
                                             > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051234) establishment of localization [1959, 0][dist]
               > (GO:0046903) secretion [97, 0][dist]
                     > (GO:0032940) secretion by cell [97, 0][dist]
                           > (GO:0045045) secretory pathway [61, 2 ][dist]
                                 > (GO:0006887) exocytosis [21, 3 ][dist]
                                       > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                             > (GO:0007340) acrosome reaction [0,0]
                                                   > (GO:0002077) acrosome matrix dispersal [0,0]

   > (GO:0008150) biological_process [10287, 0][dist]
         > (GO:0051234) establishment of localization [1959, 0][dist]
               > (GO:0051649) establishment of cellular localization [477, 0][dist]
                     > (GO:0032940) secretion by cell [97, 0][dist]
                           > (GO:0045045) secretory pathway [61, 2 ][dist]
                                 > (GO:0006887) exocytosis [21, 3 ][dist]
                                       > (GO:0017156) calcium ion-dependent exocytosis [0,0]
                                             > (GO:0007340) acrosome reaction [0,0]
                                                   > (GO:0002077) acrosome matrix dispersal [0,0]